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Inflammatory caspases (caspases 1, 4, 5 and 11) are activated in response to microbial infection and danger signals. When… Expand Phosphatidic acid (PtdOH) is emerging as an important signaling lipid in abiotic stress responses in plants. The effect of cold… Expand Eleven distinct isoforms of phosphoinositide-specific phospholipase C (PLC), which are grouped into four subfamilies (beta, gamma… Expand Tissue injury generates endogenous factors that heighten our sense of pain by increasing the response of sensory nerve endings to… Expand OBJECTIVE
Inadequate assessment of pain in premature infants is a persistent clinical problem. The objective of this research was… Expand Phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) is rapidly produced upon exposure of neutrophils to the chemoattractant N… Expand A class of membrane molecules has been identified whose primary translation product includes a COOH-terminal protein sequence… Expand There has recently been rapid progress in understanding receptors that generate intracellular signals from inositol lipids. One… Expand Activation of receptors for a wide variety of hormones and neurotransmitters leads to an increase in the intracellular level of… Expand The agonist-dependent hydrolysis of inositol phospholipids was investigated by studying the breakdown of prelabelled lipid or by… Expand