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Phosphatidylinositols

Known as: Phospholipids, Inositide, inositol phospholipid, Phosphoglycerides, Inositol 
A phosphatidic acid combined with inositol found in biomembranes and a precursor to certain cellular signals. Sometimes referred to as inositide. It… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (19)

1,2-dioleoylphosphatidylinositolGlycosylphosphatidylinositolsPIP3-APBPhosphatidylinositol Phosphates
CDIPT geneDietary PhosphatidylinositolIn BloodInositol Phosphates

Broader (3)

GlycerophospholipidsGlycolipidsPhosphatidic Acid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression
Highly Cited
2007
Highly Cited
2007
Nucleocytoplasmic Shuttling of the NAD+-dependent Histone Deacetylase SIRT1*
Sir2 (silent information regulator 2) is an NAD+-dependent histone deacetylase that contributes to longevity in yeast. SIRT1, a… 
Highly Cited
2000
Highly Cited
2000
A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
The microbially derived antiproliferative agent rapamycin inhibits cell growth by interfering with the signaling functions of the… 
Review
1999
Review
1999
Signaling by distinct classes of phosphoinositide 3-kinases.
Many signaling pathways converge on and regulate phosphoinositide 3-kinase (PI3K) enzymes whose inositol lipid products are key… 
Highly Cited
1998
Highly Cited
1998
LAT The ZAP-70 Tyrosine Kinase Substrate that Links T Cell Receptor to Cellular Activation
Highly Cited
1997
Highly Cited
1997
Matrix adhesion and Ras transformation both activate a phosphoinositide 3‐OH kinase and protein kinase B/Akt cellular survival pathway
Upon detachment from the extracellular matrix, epithelial cells enter into programmed cell death, a phenomenon known as anoikis… 
Highly Cited
1997
Highly Cited
1997
Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis
Inositol phospholipids play multiple roles in cell signalling systems. Two widespread eukaryotic phosphoinositide-based signal… 
Highly Cited
1995
Highly Cited
1995
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase.
Phosphoinositide-3 kinase activity is implicated in diverse cellular responses triggered by mammalian cell surface receptors and… 
Highly Cited
1994
Highly Cited
1994
ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
Conflicting results concerning the ability of the epidermal growth factor (EGF) receptor to associate with and/or activate… 
Review
1992
Review
1992
Regulation of inositol phospholipid-specific phospholipase C isozymes.
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