Semantic Scholar uses AI to extract papers important to this topic.
Phosphoinositide-specific phospholipase C is an effector molecule in the signal transduction process. It generates two second… Expand Eleven distinct isoforms of phosphoinositide-specific phospholipase C (PLC), which are grouped into four subfamilies (beta, gamma… Expand Phosphoinositide-specific phospholipase C (PLC) subtypes beta, gamma, and delta comprise a related group of multidomain… Expand The linker molecule LAT is a critical substrate of the tyrosine kinases activated upon TCR engagement. Phosphorylated LAT binds… Expand A variety of extracellular signals are transduced across the cell membrane by the enzyme phosphoinositide-specific phospholipase… Expand The X-ray crystal structure of the high affinity complex between the pleckstrin homology (PH) domain from rat phospholipase C… Expand A variety of pathogenic bacteria produce phospholipases C, and since the discovery in 1944 that a bacterial toxin (Clostridium… Expand In this paper, we describe a phospholipid transmission pathway mediating tumor necrosis factor (TNF) activation of the nuclear… Expand HYDROLYSIS by phospholipase C (PLC) of phosphatidylinositol 4,5-bisphosphate is a key mechanism by which many extracellular… Expand Severe norpA mutations in Drosophila eliminate the photoreceptor potential and render the fly completely blind. Recent… Expand