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Phospholipase C

Known as: phosphatidylcholine cholinephosphohydrolase, alpha-toxin, PLC 
An enzyme found in the alpha-toxin of Clostridium welchii and other strains of clostridia and bacilli. It hydrolyzes glycerophosphatidates with the… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
It is well known that brain-derived neurotrophic factor, BDNF, has an important role in a variety of neuronal aspects, such as… Expand
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Highly Cited
2009
Highly Cited
2009
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has recently emerged worldwide. The United States, in… Expand
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Review
2004
Review
2004
The incidence of Clostridium perfringens-associated necrotic enteritis in poultry has increased in countries that stopped using… Expand
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Highly Cited
2003
Highly Cited
2003
Signals transduced by kinases depend on the extent and duration of substrate phosphorylation. We generated genetically encoded… Expand
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Review
2001
Review
2001
  • Sue Goo Rhee
  • Annual review of biochemistry
  • 2001
  • Corpus ID: 21158219
Eleven distinct isoforms of phosphoinositide-specific phospholipase C (PLC), which are grouped into four subfamilies (beta, gamma… Expand
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Highly Cited
2001
Highly Cited
2001
The advent of transcription profiling technologies has provided researchers with an unprecedented ability to study biological… Expand
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Highly Cited
1998
Highly Cited
1998
The linker molecule LAT is a critical substrate of the tyrosine kinases activated upon TCR engagement. Phosphorylated LAT binds… Expand
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Highly Cited
1995
Highly Cited
1995
The X-ray crystal structure of the high affinity complex between the pleckstrin homology (PH) domain from rat phospholipase C… Expand
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Highly Cited
1992
Highly Cited
1992
In this paper, we describe a phospholipid transmission pathway mediating tumor necrosis factor (TNF) activation of the nuclear… Expand
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Highly Cited
1988
Highly Cited
1988
Severe norpA mutations in Drosophila eliminate the photoreceptor potential and render the fly completely blind. Recent… Expand
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