Phospholipase C

Known as: phosphatidylcholine cholinephosphohydrolase, alpha-toxin, PLC 
An enzyme found in the alpha-toxin of Clostridium welchii and other strains of clostridia and bacilli. It hydrolyzes glycerophosphatidates with the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1940-2017
020040019402016

Papers overview

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Highly Cited
2005
Highly Cited
2005
We have further tested the hypothesis that receptor-mediated modulation of KCNQ channels involves depletion of… (More)
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Highly Cited
2004
Highly Cited
2004
The epidermal growth factor (EGF)-induced increase in free barbed ends, resulting in actin polymerization at the leading edge of… (More)
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Highly Cited
2001
Highly Cited
2001
Tissue injury generates endogenous factors that heighten our sense of pain by increasing the response of sensory nerve endings to… (More)
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Highly Cited
1997
Highly Cited
1997
A variety of extracellular signals are transduced across the cell membrane by the enzyme phosphoinositide-specific phospholipase… (More)
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Highly Cited
1995
Highly Cited
1995
The X-ray crystal structure of the high affinity complex between the pleckstrin homology (PH) domain from rat phospholipase C… (More)
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Highly Cited
1995
Highly Cited
1995
Listeria monocytogenes secretes two distinct phospholipases C, a phosphatidylinositol-specific phospholipase C (PI-PLC) and a… (More)
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Highly Cited
1992
Highly Cited
1992
In this paper, we describe a phospholipid transmission pathway mediating tumor necrosis factor (TNF) activation of the nuclear… (More)
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Highly Cited
1991
Highly Cited
1991
The making and sealing of a tight junction (TJ) requires cell-cell contacts and Ca2−, and can be gauged through the development… (More)
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Highly Cited
1990
Highly Cited
1990
1-[6-[[17 beta-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]- 1H-pyrrole-2,5-dione (U-73122), an inhibitor of phospholipase C… (More)
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Highly Cited
1988
Highly Cited
1988
Severe norpA mutations in Drosophila eliminate the photoreceptor potential and render the fly completely blind. Recent… (More)
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