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Peptidyl-Dipeptidase A

Known as: Kininase II, Peptidyl Dipeptidase A, angiotensin converting enzymes 
A peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent… 
National Institutes of Health

Related topics

Related topics

23 relations
ACE SerPl-cCncACE geneACE wt AlleleACE2 gene

Narrower (2)

ACE protein, humanangiotensin converting enzyme 2

Broader (2)

Renin-angiotensin systempeptidyl dipeptidase

Papers overview

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Highly Cited
1995
Highly Cited
1995
A simple molecular assay for the C1166 variant of the angiotensin II type 1 receptor gene.
Studies of human polygenic diseases require the genotyping of polymorphic markers from large numbers of subjects. The rapid… 
Review
1995
Review
1995
Angiotensin converting enzyme inhibitors, left ventricular hypertrophy and fibrosis
From pharmacological investigations and clinical studies, it is known that angiotensin converting enzyme (ACE) inhibitors exhibit… 
Review
1995
Review
1995
Main objectives and new aspects of combination treatment of hypertension
Aim: To review the various pharmacological approaches currently proposed for the treatment of hypertension. Results: With the… 
1993
1993
A new genetic locus cosegregating with blood pressure in F2 progeny obtained from stroke-prone spontaneously hypertensive rats and Wistar-Kyoto rats
Background: Segregation studies using genomic polymorphisms on F2 progeny obtained from hypertensive rat models showed that a… 
Highly Cited
1986
Highly Cited
1986
Conformationally restricted inhibitors of angiotensin converting enzyme: synthesis and computations.
A series of inhibitors of angiotensin converting enzyme (ACE, dipeptidyl carboxypeptidase, EC 3.4.15.1) is described which… 
1986
1986
Identification of a transformation-sensitive 110-kDa plasma membrane glycoprotein of rat hepatocytes.
Monoclonal antibodies were used to define cell surface antigens which are present on rat hepatocytes but are absent from hepatoma… 
1983
1983
Inhibition of angiotensin converting enzyme by phosphonic amides and phosphonic acids.
1981
1981
Inactivation of substance P and its C-terminal fragments in rat plasma and its inhibition by Captopril.
The metabolic degradation of substance P(SP), some of its C-terminal fragments, and some analogues by rat plasma has been… 
Highly Cited
1980
Highly Cited
1980
Effect of acute lung injury on angiotensin converting enzyme in serum, lung lavage, and effusate.
The administration of an acute pulmonary edemagenic dose (ip) of thiourea to rats results in an elevation of angiotensin… 
1979
1979
Clinical significance of serum angiotensin-converting enzyme levels in sarcoidosis.
Determinations of SACE activity were performed in 80 patients with sarcoidosis, 55 normal controls, and 29 patients with asthma…