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Peptidyl-Dipeptidase A

Known as: Kininase II, Peptidyl Dipeptidase A, angiotensin converting enzymes 
A peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent… 
National Institutes of Health

Related topics

Related topics

23 relations
ACE SerPl-cCncACE geneACE wt AlleleACE2 gene

Narrower (2)

ACE protein, humanangiotensin converting enzyme 2

Broader (2)

Renin-angiotensin systempeptidyl dipeptidase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Deletion of Angiotensin-Converting Enzyme 2 Accelerates Pressure Overload–Induced Cardiac Dysfunction by Increasing Local Angiotensin II
Angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase that cleaves angiotensin II to angiotensin 1-7. Recently, it was… 
Highly Cited
2005
Highly Cited
2005
Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction.
Highly Cited
1998
Highly Cited
1998
Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II.
The classically recognized functions of the renin-angiotensin system are mediated by type 1 (AT1) angiotensin receptors. Whereas… 
Highly Cited
1996
Highly Cited
1996
Two-way cell traffic between mother and fetus: biologic and clinical implications.
The bilateral trafficking of nucleated cells between the fetus and the mother was studied using polymerase chain reaction (PCR… 
Review
1995
Review
1995
Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors.
From pharmacological investigations and clinical studies, it is known that ACE inhibitors exhibit additional local actions that… 
Highly Cited
1993
Highly Cited
1993
Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death
Highly Cited
1993
Highly Cited
1993
Angiotensin-converting enzyme DD genotype in patients with ischaemic or idiopathic dilated cardiomyopathy
Highly Cited
1986
Highly Cited
1986
Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM1215).
The effects of short chain fatty acids on a colon carcinoma cell line, LIM1215, have been studied. Of the four short chain fatty… 
Highly Cited
1980
Highly Cited
1980
The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice
There is both theoretical and therapeutic interest in establishing whether the signals conveyed by the enkephalins are turned off… 
Highly Cited
1977
Highly Cited
1977
A SPECIFIC ORALLY ACTIVE INHIBITOR OF ANGIOTENSIN-CONVERTING ENZYME IN MAN
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