angiotensin converting enzyme 2

Known as: Angiotensin-Converting Enzyme 2, EC 3.4.17.23, ACEH 
Angiotensin-converting enzyme 2 (805 aa, ~92 kDa) is encoded by the human ACE2 gene. This protein plays a role in both vasodilation and protein… (More)
National Institutes of Health

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12 relations
ACE2 geneAngiotensin-converting Enzyme 2 PathwayEnzyme GeneExtracellular Space
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Broader (1)

Peptidyl-Dipeptidase A

Papers overview

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Highly Cited
2010
Highly Cited
2010
Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction.
BACKGROUND Angiotensin-converting enzyme 2 (ACE2) is a pleiotropic monocarboxypeptidase capable of metabolizing several peptide… (More)
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Highly Cited
2006
Highly Cited
2006
Glomerular localization and expression of Angiotensin-converting enzyme 2 and Angiotensin-converting enzyme: implications for albuminuria in diabetes.
Angiotensin-converting enzyme 2 (ACE2) expression has been shown to be altered in renal tubules from diabetic mice. This study… (More)
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Highly Cited
2005
Highly Cited
2005
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury
During several months of 2003, a newly identified illness termed severe acute respiratory syndrome (SARS) spread rapidly through… (More)
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Highly Cited
2005
Highly Cited
2005
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2.
BACKGROUND Angiotensin-converting enzyme 2 (ACE2) has emerged as a novel regulator of cardiac function and arterial pressure by… (More)
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Highly Cited
2003
Highly Cited
2003
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.
Spike (S) proteins of coronaviruses, including the coronavirus that causes severe acute respiratory syndrome (SARS), associate… (More)
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Highly Cited
2003
Highly Cited
2003
Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy.
ACE2, initially cloned from a human heart, is a recently described homologue of angiotensin-converting enzyme (ACE) but contains… (More)
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Highly Cited
2002
Highly Cited
2002
Angiotensin-converting enzyme 2 is an essential regulator of heart function
Cardiovascular diseases are predicted to be the most common cause of death worldwide by 2020. Here we show that angiotensin… (More)
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Highly Cited
2002
Highly Cited
2002
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase.
Human angiotensin-converting enzyme-related carboxypeptidase (ACE2) is a zinc metalloprotease whose closest homolog is… (More)
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Highly Cited
2000
Highly Cited
2000
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9.
ACE2, the first known human homologue of angiotensin-converting enzyme (ACE), was identified from 5' sequencing of a human heart… (More)
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Highly Cited
2000
Highly Cited
2000
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase.
A novel human zinc metalloprotease that has considerable homology to human angiotensin-converting enzyme (ACE) (40% identity and… (More)
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