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PTK2B gene

Known as: PROTEIN-TYROSINE KINASE 2, BETA, FAK2, FOCAL ADHESION KINASE 2 
This gene is involved in signal transduction and the regulation of ion channels.
National Institutes of Health

Related topics

Related topics

13 relations
ApoptosisCell Differentiation processCell ProliferationHomo sapiens

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PTK2B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-CateninY654
2018
2018
A novel role for PTK2B in cultured beige adipocyte differentiation.
2017
2017
Sperm-oocyte contact induces outside-in signaling via PYK2 activation.
2012
2012
Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors.
2008
2008
Protein-tyrosine kinase CAKbeta/PYK2 is activated by binding Ca2+/calmodulin to FERM F2 alpha2 helix and thus forming its dimer.
CAKbeta (cell adhesion kinase beta)/PYK2 (proline-rich tyrosine kinase 2) is the second protein-tyrosine kinase of the FAK (focal… 
2001
2001
PYK2 as a Mediator of Endothelin-1/Gα11Signaling to GLUT4 Glucose Transporters*
Endothelin-1 (ET-1) signaling through Gαq/11 stimulates translocation of intracellular GLUT4 glucose transporters to the plasma… 
2001
2001
Regulation of tyrosine phosphorylation of PYK2 in vascular endothelial cells by lysophosphatidylcholine.
Lysophosphatidylcholine (LPC), a component of oxidized low-density lipoprotein, exerts various biological effects on vascular… 
Highly Cited
1998
Highly Cited
1998
Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor.
Several G protein-coupled receptors are known to direct the tyrosine phosphorylation, and in some cases the activation, of… 
Highly Cited
1998
Highly Cited
1998
A Calcium-dependent Tyrosine Kinase Splice Variant in Human Monocytes
Freshly isolated human monocytes do not express p125FAK but upon adherence to substrata activate the highly related calcium… 
Highly Cited
1997
Highly Cited
1997
Tyrosine Phosphorylation of Pyk2 Is Selectively Regulated by Fyn During TCR Signaling
The Src family protein tyrosine kinases (PTKs), Lck and Fyn, are coexpressed in T cells and perform crucial functions involved in… 
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