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PPARA wt Allele

Known as: PPARalpha, NR1C1, Peroxisome Proliferator-Activated Receptor Alpha wt Allele 
Human PPARA wild-type allele is located within 22q12-q13.1 and is approximately 93 kb in length. This allele, which encodes peroxisome proliferator… 
National Institutes of Health

Related topics

Related topics

20 relations
Adipocytokine Signaling PathwayBiologic DevelopmentCell Differentiation processCell Proliferation

Narrower (2)

PPAR alphaPeroxisome Proliferator-Activated Receptors

Broader (1)

PPARA gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
MicroRNAs-Dependent Regulation of PPARs in Metabolic Diseases and Cancers
Peroxisome proliferator-activated receptors (PPARs) are a family of ligand-dependent nuclear receptors, which control the… 
2009
2009
Opposing Roles of Peroxisome Proliferator-activated Receptor α and Growth Hormone in the Regulation of CYP4A11 Expression in a Transgenic Mouse Model*
CYP4A11 transgenic mice (CYP4A11 Tg) were generated to examine in vivo regulation of the human CYP4A11 gene. Expression of… 
Highly Cited
2007
Highly Cited
2007
PPARalpha is a potential therapeutic target of drugs to treat circadian rhythm sleep disorders.
2007
2007
Peroxisome Proliferator–Activated Receptor α Protects against Glomerulonephritis Induced by Long-Term Exposure to the Plasticizer Di-(2-Ethylhexyl)Phthalate
Safety concerns about di-(2-ethylhexyl)phthalate (DEHP), a plasticizer and a probable endocrine disruptor, have attracted… 
Highly Cited
2004
Highly Cited
2004
The Transcriptional Response to a Peroxisome Proliferator-activated Receptor α Agonist Includes Increased Expression of Proteome Maintenance Genes*
The nuclear receptor peroxisome proliferator-activated receptor α (PPARα), in addition to regulating lipid homeostasis, controls… 
Review
2004
Review
2004
An overview of the effect of linoleic and conjugated‐linoleic acids on the growth of several human tumor cell lines
Both n‐6 and n‐3 polyunsaturated fatty acids are dietary fats important for cell function, being involved in several physiologic… 
Highly Cited
2003
Highly Cited
2003
The anti-apoptotic role of PPARβ contributes to efficient skin wound healing
Review
2001
Review
2001
Peroxisome Proliferator-Activated Receptors and Skin Development
PPARs are nuclear hormone receptors. PPAR subtypes (α, γ, δ, the latter a xPPARβ homologue) were initially investigated in skin… 
2000
2000
Evidence for peroxisome proliferator-activated receptor (PPAR)alpha-independent peroxisome proliferation: effects of PPARgamma/delta-specific agonists in PPARalpha-null mice.
Peroxisome proliferators are a diverse group of compounds that cause hepatic hypertrophy and hyperplasia, increase peroxisome… 
2000
2000
Frequency of stromal lineage colony forming units in bone marrow of peroxisome proliferator-activated receptor-alpha-null mice.
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