PPARA wt Allele

Known as: PPARalpha, NR1C1, Peroxisome Proliferator-Activated Receptor Alpha wt Allele 
Human PPARA wild-type allele is located within 22q12-q13.1 and is approximately 93 kb in length. This allele, which encodes peroxisome proliferator… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The nuclear receptor PPARalpha is activated by drugs to treat human disorders of lipid metabolism. Its endogenous ligand is… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Studies in mice have shown that PPARalpha is an important regulator of hepatic lipid metabolism and the acute phase… (More)
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Highly Cited
2007
Highly Cited
2007
This study evaluates the potential for perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) to activate peroxisome… (More)
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Highly Cited
2007
Highly Cited
2007
Recently it has become evident that obesity is associated with low-grade chronic inflammation. The transcription factor… (More)
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Highly Cited
2006
Highly Cited
2006
Recent evidence has emerged that peroxisome proliferator-activated receptor alpha (PPARalpha), which is largely involved in lipid… (More)
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Review
2001
Review
2001
The peroxisome proliferator-activated receptors (PPARalpha, gamma, delta) are members of the nuclear receptor superfamily of… (More)
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Highly Cited
2001
Highly Cited
2001
We examined the effects of a variety of ligands/activators of the peroxisome proliferator-activated receptor (PPAR) on the… (More)
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Highly Cited
2001
Highly Cited
2001
Hypoxia triggers a cascade of cellular energy metabolic responses including a decrease in mitochondrial oxidative flux. To… (More)
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Highly Cited
2000
Highly Cited
2000
The peroxisome proliferator-activated receptor alpha (PPARalpha) is a member of the nuclear receptor superfamily and mediates the… (More)
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Highly Cited
2000
Highly Cited
2000
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a member of the steroid hormone receptor super family involved in… (More)
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