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PPARA wt Allele

Known as: PPARalpha, NR1C1, Peroxisome Proliferator-Activated Receptor Alpha wt Allele 
Human PPARA wild-type allele is located within 22q12-q13.1 and is approximately 93 kb in length. This allele, which encodes peroxisome proliferator… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The nuclear receptor PPARalpha is activated by drugs to treat human disorders of lipid metabolism. Its endogenous ligand is… Expand
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Highly Cited
2008
Highly Cited
2008
Histone deacetylase (HDAC) inhibitors show remarkable therapeutic potential for a variety of disorders, including cancer… Expand
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Highly Cited
2006
Highly Cited
2006
Recent evidence has emerged that peroxisome proliferator-activated receptor alpha (PPARalpha), which is largely involved in lipid… Expand
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Highly Cited
2003
Highly Cited
2003
Abstract— Long-chain fatty acids (FA) coordinately induce the expression of a panel of genes involved in cellular FA metabolism… Expand
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Review
2003
Review
2003
Widely varied chemicals--including certain herbicides, plasticizers, drugs, and natural products--induce peroxisome proliferation… Expand
Review
2001
Review
2001
The peroxisome proliferator-activated receptors (PPARalpha, gamma, delta) are members of the nuclear receptor superfamily of… Expand
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Highly Cited
2001
Highly Cited
2001
We show here that the α, β, and γ isotypes of peroxisome proliferator–activated receptor (PPAR) are expressed in the mouse… Expand
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Highly Cited
2000
Highly Cited
2000
The peroxisome proliferator-activated receptor α (PPARα) is a member of the nuclear receptor superfamily and mediates the… Expand
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Highly Cited
2000
Highly Cited
2000
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a member of the steroid hormone receptor super family involved in… Expand
Highly Cited
1996
Highly Cited
1996
Increased activity of lipoprotein lipase (LPL) may explain the hypotriglyceridemic effects of fibrates, thiazolidinediones and… Expand