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Adipose-derived stem cells for regenerative medicine.
The emerging field of regenerative medicine will require a reliable source of stem cells in addition to biomaterial scaffolds and cytokine growth factors. Adipose tissue represents an abundant and… Expand
Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose…
BACKGROUND AIMS Adipose tissue is a rich and very convenient source of cells for regenerative medicine therapeutic approaches. However, a characterization of the population of adipose-derived stromal… Expand
Immunophenotype of Human Adipose‐Derived Cells: Temporal Changes in Stromal‐Associated and Stem Cell–Associated Markers
Adipose tissue represents an abundant and accessible source of multipotent adult stem cells and is used by many investigators for tissue engineering applications; however, not all laboratories use… Expand
Control of stem cell fate by physical interactions with the extracellular matrix.
- F. Guilak, D. Cohen, B. T. Estes, J. Gimble, W. Liedtke, C. Chen
- Biology, Medicine
- Cell stem cell
- 2 July 2009
A diverse array of environmental factors contributes to the overall control of stem cell activity. In particular, new data continue to mount on the influence of the extracellular matrix (ECM) on stem… Expand
Yield of human adipose-derived adult stem cells from liposuction aspirates.
BACKGROUND Primary cultures of isolated human adipose-derived adult stem (ADAS) cells are multipotent and differentiate in vitro along the adipocyte, chondrocyte, neuronal, osteoblast, and skeletal… Expand
Cytokine profile of human adipose‐derived stem cells: Expression of angiogenic, hematopoietic, and pro‐inflammatory factors
- G. Kilroy, S. Foster, +11 authors J. Gimble
- Medicine, Biology
- Journal of cellular physiology
- 1 September 2007
Adipose tissue serves as a source of adipokines and cytokines with both local and systemic actions in health and disease. In this study, we examine the hypothesis that multipotent human… Expand
Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype
The ability to isolate, expand and differentiate adult stem cells into a chondrogenic lineage is an important step in the development of tissue engineering approaches for cartilage repair or… Expand
Neurogenic differentiation of murine and human adipose-derived stromal cells.
- K. M. Safford, K. Hicok, +4 authors H. Rice
- Biology, Medicine
- Biochemical and biophysical research…
- 7 June 2002
The identification of cells capable of neuronal differentiation has great potential for cellular therapies. We examined whether murine and human adipose-derived adult stem (ADAS) cells can be induced… Expand
The Immunogenicity of Human Adipose‐Derived Cells: Temporal Changes In Vitro
Regenerative medical techniques will require an abundant source of human adult stem cells that can be readily available at the point of care. The ability to use unmatched allogeneic stem cells will… Expand
Characterization of peripheral circadian clocks in adipose tissues.
First described in the suprachiasmatic nucleus, circadian clocks have since been found in several peripheral tissues. Although obesity has been associated with dysregulated circadian expression… Expand