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Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome.
OBJECTIVE NIDDM occurs commonly among women with polycystic ovary syndrome (PCOS). The prevalence and natural history of its precursor, impaired glucose tolerance (IGT), is less well known. TheExpand
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Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome.
  • D. Ehrmann, D J Schneider, +4 authors K. Polonsky
  • Biology, Medicine
  • The Journal of clinical endocrinology and…
  • 1 July 1997
Women with polycystic ovary syndrome (PCOS) are characterized by defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis. We administered the insulin-sensitizing agentExpand
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The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited.
Polycystic ovary syndrome (PCOS) was hypothesized to result from functional ovarian hyperandrogenism (FOH) due to dysregulation of androgen secretion in 1989-1995. Subsequent studies have supportedExpand
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Evaluation and treatment of hirsutism in premenopausal women: an endocrine society clinical practice guideline.
OBJECTIVE Our objective was to develop clinical practice guidelines for the evaluation and treatment of hirsutism in premenopausal women. PARTICIPANTS The Task Force was composed of a chair,Expand
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Hirsutism: implications, etiology, and management.
Hirsutism usually results from a subtle excess of androgens. As such, it is a clue to possible endocrine disturbance in addition to presenting cosmetic problems. We use the term hirsutism to meanExpand
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Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion.
I. History and Terminology: From Stein-Leventhal toFunctional Ovarian Hyperandrogenism (FOH) IN 1935, Stein and Leventhal (1) reported the association of polycystic ovaries in women with amenorrhea,Expand
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Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus.
The increased prevalence of non-insulin-dependent diabetes mellitus (NIDDM) among women with polycystic ovary syndrome (PCOS) has been ascribed to the insulin resistance characteristic of PCOS. ThisExpand
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Role of hormones in pilosebaceous unit development.
Androgens are required for sexual hair and sebaceous gland development. However, pilosebaceous unit (PSU) growth and differentiation require the interaction of androgen with numerous other biologicalExpand
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Clinical review: Identifying children at risk for polycystic ovary syndrome.
  • R. Rosenfield
  • Medicine
  • The Journal of clinical endocrinology and…
  • 1 March 2007
CONTEXT Polycystic ovary syndrome (PCOS) appears to arise as a complex trait with contributions from both heritable and nonheritable factors. Polygenic influences appear to account for about 70% ofExpand
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The Diagnosis of Polycystic Ovary Syndrome during Adolescence
Background/Aims: The diagnostic criteria for polycystic ovary syndrome (PCOS) in adolescence are controversial, primarily because the diagnostic pathological features used in adult women may beExpand
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