Skip to search formSkip to main contentSkip to account menu

PPAR alpha

Known as: Peroxisome Proliferator Activated Receptor alpha, PPARalpha, Peroxisome Proliferator-Activated Receptor Alpha 
Peroxisome proliferator-activated receptor alpha (468 aa, ~52 kDa) is encoded by the human PPARA gene. This protein is involved in cell proliferation… 
National Institutes of Health

Related topics

Related topics

44 relations
Adipocytokine Signaling PathwayBiologic DevelopmentCell Differentiation processCell Nucleus

Broader (1)

PPARA wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Regulation of Sulfotransferase Enzymes by Prototypical Microsomal Enzyme Inducers in Mice
In the present study, the regulation of the mRNA of 11 sulfotransferases (Sults) and two 3′-phosphoadenosine 5′-phosphosulfate… 
Highly Cited
2005
Highly Cited
2005
Hepatitis C virus infection down-regulates the expression of peroxisome proliferator-activated receptor alpha and carnitine palmitoyl acyl-CoA transferase 1A.
AIM To elucidate the role of the peroxisome proliferator-activated receptor alpha (PPARalpha) and its target gene carnitine… 
Highly Cited
2004
Highly Cited
2004
Up-regulation of p21 Gene Expression by Peroxisome Proliferator-Activated Receptor γ in Human Lung Carcinoma Cells
Purpose: The peroxisome proliferator-activated receptor γ (PPARγ), a ligand-dependent transcription factor belonging to the… 
Highly Cited
2004
Highly Cited
2004
Statin Induction of Liver Fatty Acid-Binding Protein (L-FABP) Gene Expression Is Peroxisome Proliferator-activated Receptor-α-dependent*
Statins are drugs widely used in humans to treat hypercholesterolemia. Statins act by inhibiting cholesterol synthesis resulting… 
Highly Cited
2004
Highly Cited
2004
The Transcriptional Response to a Peroxisome Proliferator-activated Receptor α Agonist Includes Increased Expression of Proteome Maintenance Genes*
The nuclear receptor peroxisome proliferator-activated receptor α (PPARα), in addition to regulating lipid homeostasis, controls… 
Highly Cited
2002
Highly Cited
2002
The Gene Encoding the Acyl-CoA-binding Protein Is Activated by Peroxisome Proliferator-activated Receptor γ through an Intronic Response Element Functionally Conserved between Humans and Rodents*
The acyl-CoA-binding protein (ACBP) is a 10-kDa intracellular protein that specifically binds acyl-CoA esters with high affinity… 
Highly Cited
2001
Highly Cited
2001
The 5'-flanking regions of CYP19A1 and CYP19A2 in zebrafish.
This report describes the structure of the 5'-flanking regions of both the CYP19A1 and A2 genes that were isolated from the… 
Highly Cited
2000
Highly Cited
2000
Expression of peroxisome proliferator‐activated receptors (PPARS) in human astrocytic cells: PPARγ agonists as inducers of apoptosis
We report the isolation by RT‐PCR of partial cDNAs encoding the human peroxisome proliferator‐activated receptor (PPAR) isoforms… 
Highly Cited
1999
Highly Cited
1999
The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences in response to PPs.
Peroxisome proliferators (PP) cause peroxisome proliferation, associated with rodent hepatocyte growth perturbation and… 
Highly Cited
1999
Highly Cited
1999
L-764406 Is a Partial Agonist of Human Peroxisome Proliferator-activated Receptor γ
Insulin-sensitizing thiazolidinedione (TZD) compounds are high affinity ligands for a member of the nuclear receptor family… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)