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PNOC wt Allele

Known as: N/OFQ, PPNOC, OFQ 
Human PNOC wild-type allele is located in the vicinity of 8p21 and is approximately 26 kb in length. This allele, which encodes prepronociceptin… Expand
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Members of the opioid receptor family of G-protein-coupled receptors (GPCRs) are found throughout the peripheral and central… Expand
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Highly Cited
2008
Highly Cited
2008
  • D G Lambert
  • Nature Reviews Drug Discovery
  • 2008
  • Corpus ID: 7466788
Identification of the enigmatic nociceptin/orphanin FQ peptide (N/OFQ) in 1995 represented the first successful use of reverse… Expand
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Highly Cited
2005
Highly Cited
2005
Salvinorin A, TRK-820 (17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[N-methyl-trans-3-(3-furyl) acrylamido]morphinan… Expand
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Highly Cited
2001
Highly Cited
2001
Abstract This study evaluated the accuracy of several models for estimating daily solar radiation ( Q ) across Australia. Data… Expand
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Highly Cited
2000
Highly Cited
2000
Orphanin FQ/nociceptin (OFQ/N) and its receptor share substantial structural features and cellular actions with classic opioid… Expand
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Highly Cited
1999
Highly Cited
1999
The recently discovered neuropeptide orphanin FQ (OFQ), and its opioid receptor-like (ORL1) receptor, exhibit structural features… Expand
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Highly Cited
1999
Highly Cited
1999
Orphanin FQ (OFQ) is the endogenous agonist of the opioid receptor-like receptor (ORL-1). It and its precursor, prepro-OFQ… Expand
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Highly Cited
1999
Highly Cited
1999
The neuropeptide orphanin FQ (also known as nociceptin; OFQ/N) has been implicated in modulating stress-related behavior. OFQ/N… Expand
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Review
1998
Review
1998
The publication of the delta opioid receptor sequence led to the cloning of three homologous receptors: the mu and kappa opioid… Expand
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Highly Cited
1997
Highly Cited
1997
Orphanin FQ (OFQ, Nociceptin) is a recently discovered 17-amino acid neuropeptide that is structurally related to the opioid… Expand
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