• Publications
  • Influence
Effect of octreotide on intestinal motility and bacterial overgrowth in scleroderma.
TLDR
Octreotide stimulates intestinal motility in normal subjects and in patients with scleroderma, and reduces bacterial overgrowth and improves abdominal symptoms, suggesting that intestinal activity evoked by octreotide is independent of motilin. Expand
Serum glucose concentration as a modulator of interdigestive gastric motility.
TLDR
It is concluded that hyperglycemia inhibits the occurrence of the MMC in the stomach and suppresses plasma motilin levels, suggesting that the antral and duodenal MMCs are mediated by different mechanisms. Expand
Intestinal serotonin acts as a paracrine substance to mediate vagal signal transmission evoked by luminal factors in the rat
TLDR
The results suggested that the nodose neuronal responses to luminal osmolarity and to the digestion products of carbohydrates are dependent on the release of endogenous 5‐HT from the mucosal enterochromaffin cells, which acts on the5‐HT3 receptors on vagal afferent fibres to stimulate vagal sensory neurons. Expand
The influence of the interdigestive migrating myoelectric complex on the gastric emptying of liquids.
TLDR
This study shows a strong dependence of liquid gastric emptying rate and lag time on interdigestive antral motility, the emptying of small volumes being more dependent on motility phase than that of large volumes. Expand
Enhanced responses of the anterior cingulate cortex neurones to colonic distension in viscerally hypersensitive rats
TLDR
It is established for the first time that persistence of a heightened visceral afferent nociceptive input to the ACC induces ACC sensitization, characterized by increased spontaneous activity of CRD‐excited neurones, decreased CRD pressure threshold, and increased response magnitude. Expand
Characterization of vagal pathways mediating gastric accommodation reflex in rats
TLDR
It is suggested that the vago‐vagal reflex plays an important role in mediating the accommodation reflex following vagotomy, and a vagal efferent pathway that uses nitric oxide as a final neurotransmitter mediating gastric relaxation in intact rats is suggested. Expand
Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection.
TLDR
Ginger effectively reduces nausea, tachygastric activity, and vasopressin release induced by circular vection and may act as a novel agent in the prevention and treatment of motion sickness. Expand
New insights into neurohormonal regulation of pancreatic secretion.
TLDR
Structural and functional evidence suggests that CCK acts on vagal afferent fibers, which may explain how CCK doses that produce physiologic plasma CCK levels act via vagal cholinergic pathways to stimulate pancreatic secretion. Expand
Rifaximin alters intestinal bacteria and prevents stress-induced gut inflammation and visceral hyperalgesia in rats.
TLDR
Rifaximin alters the bacterial population in the ileum of rats, leading to a relative abundance of Lactobacillus, which prevents intestinal abnormalities and visceral hyperalgesia in response to chronic psychological stress. Expand
Role of plasma vasopressin as a mediator of nausea and gastric slow wave dysrhythmias in motion sickness.
TLDR
It is concluded that vection evokes nausea, dysrhythmias, and vasopressin release in motion sickness-susceptible humans via cholinergic prostaglandin-independent pathways and central but not peripheral actions of vasoppressin may contribute to nausea and slow wave disruption with vection. Expand
...
1
2
3
4
5
...