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Ouabain

Known as: Ouabain anhydrous, Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-1,5,11,14,19-pentahydroxy-, (1beta,3beta,5beta,11alpha)-, G-Strophanthin 
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The sodium-potassium pump (Na+,K+-ATPase) is responsible for establishing Na+ and K+ concentration gradients across the plasma… Expand
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Highly Cited
2004
Highly Cited
2004
Based on the observation that the Na+/K+-ATPase α subunit contains two conserved caveolin-binding motifs, we hypothesized that… Expand
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Highly Cited
2001
Highly Cited
2001
The plant-derived steroid, digoxin, a specific inhibitor of Na,K-ATPase, has been used for centuries in the treatment of heart… Expand
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Highly Cited
2000
Highly Cited
2000
We have shown previously that partial inhibition of the cardiac myocyte Na(+)/K(+)-ATPase activates signal pathways that regulate… Expand
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Highly Cited
1998
Highly Cited
1998
In arteries, muscarinic agonists such as acetylcholine release an unidentified, endothelium-derived hyperpolarizing factor (EDHF… Expand
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Highly Cited
1997
Highly Cited
1997
Three isoforms (alpha1, alpha2, and alpha3) of the catalytic (alpha) subunit of the plasma membrane (PM) Na+ pump have been… Expand
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Highly Cited
1991
Highly Cited
1991
The plasma membrane sodium-potassium pumps that regulate intracellular sodium in most animal cells have specific, high-affinity… Expand
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Highly Cited
1971
Highly Cited
1971
The purpose of this study was the determination of whether hemodynamic and pharmacologic factors influence the extent and… Expand
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Highly Cited
1969
Highly Cited
1969
1. Previous work has shown that the sodium efflux from the axons of Loligo forbesi increases when external sodium is replaced by… Expand
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Highly Cited
1969
Highly Cited
1969
1. A study has been made of the cellular content and movement of Ca across the membrane of human red blood cells. 
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