Ouabain

Known as: Ouabain anhydrous, Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-1,5,11,14,19-pentahydroxy-, (1beta,3beta,5beta,11alpha)-, G-Strophanthin 
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The sodium-potassium pump (Na(+),K(+)-ATPase) is responsible for establishing Na(+) and K(+) concentration gradients across the… (More)
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Highly Cited
2007
Highly Cited
2007
We examined the regenerative capacity of the adult zebrafish retina by intravitreal injection of a low ouabain concentration to… (More)
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Highly Cited
2004
Highly Cited
2004
Based on the observation that the Na(+)/K(+)-ATPase alpha subunit contains two conserved caveolin-binding motifs, we hypothesized… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND We have demonstrated that ouabain causes dose- and time-dependent decreases in (86)Rb uptake in porcine proximal… (More)
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Highly Cited
2002
Highly Cited
2002
Binding of ouabain to Na(+)/K(+)-ATPase activates tyrosine phosphorylation of the epidermal growth factor receptor (EGFR), Src… (More)
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Highly Cited
2002
Highly Cited
2002
Energy deficiency and dysfunction of the Na+, K+-ATPase are common consequences of many pathological insults. The nature and… (More)
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Highly Cited
2001
Highly Cited
2001
The plant-derived steroid, digoxin, a specific inhibitor of Na,K-ATPase, has been used for centuries in the treatment of heart… (More)
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Highly Cited
2000
Highly Cited
2000
We have shown previously that partial inhibition of the cardiac myocyte Na(+)/K(+)-ATPase activates signal pathways that regulate… (More)
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Highly Cited
1998
Highly Cited
1998
In arteries, muscarinic agonists such as acetylcholine release an unidentified, endothelium-derived hyperpolarizing factor (EDHF… (More)
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Highly Cited
1994
Highly Cited
1994
OBJECTIVES To determine the steady-state dose-dependence of blood pressure, plasma and tissue ouabain during continuous infusion… (More)
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