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‘Classic’ cardiotonic steroids (CTSs) all inhibit Na+,K+‐ATPase (Na+ pumps) and exert cardiotonic and vasotonic effects… Expand SummaryElectrophysiological experiments were performed to analyze the Na+/K+-ATPase in full-grown prophase-arrested oocytes… Expand BACKGROUND
Ouabain-like factor (OLF) and its newly discovered reduced species, dihydroouabain-like factor (Dh-OLF), are mammalian… Expand Extra- and intracellular records were made from rat acute hippocampal slices to examine the effects of partial inhibition of Na… Expand To examine the effect of aldosterone on sarcolemmal Na+ transport, we measured ouabain-sensitive electrogenic Na(+)-K+ pump… Expand Pre-steady-state transient currents (1986. Nakao, M., and D. C. Gadsby. Nature [Lond.]. 323:628-630) mediated by the Na/K pump… Expand Binding of cardiac glycosides to the Na+,K+-dependent ATPase has been shown to occur at both high- and low-affinity sites… Expand The effects of sodium pump inhibition produced by exposure to the cardiac glycosides, ouabain or dihydroouabain, or by reduction… Expand Cardiac glycoside binding to microsomes prepared from rat heart ventricles and enriched in (Na+ + K+)-ATPase was measured by a… Expand 1 The inotropic effect of ouabain has been studied in rat ventricles and atria. 2 The concentration‐effect curve of ouabain may… Expand