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Organic Anion Transport Polypeptides
Known as:
OATP Proteins
, SLCO
, Organic Anion-Transporting Polypeptide
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A family of transmembrane proteins that play a role in the transport of organic anions including bile acids and bilirubin.
National Institutes of Health
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Related topics
Related topics
18 relations
Carrier Proteins
Cellular Membrane
Integral Membrane Proteins
Ionophore activity
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Broader (1)
Organic Anion Transporters
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Differential effect of genetic variants of Na+-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors
Min‐Koo Choi
,
H. Shin
,
Young-Lim Choi
,
Jian-Wei Deng
,
Jae-Gook Shin
,
I. Song
Xenobiotica; the fate of foreign compounds in…
2011
Corpus ID: 31358351
The purpose of this study was to investigate the effect of genetic variations in organic anion-transporting polypeptide 1B1…
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Review
2010
Review
2010
Exploring the genetic architecture of neonatal hyperbilirubinemia.
J. Watchko
,
Zhili Lin
Seminars in Fetal & Neonatal Medicine
2010
Corpus ID: 1921567
Highly Cited
2008
Highly Cited
2008
Altered expression of organic anion transporter polypeptide (OATP) genes in human breast carcinoma
Katrin Wlcek
,
M. Svoboda
,
F. Sellner
,
G. Krupitza
,
W. Jaeger
,
T. Thalhammer
Cancer Biology & Therapy
2008
Corpus ID: 32990326
Organic anion transporter polypeptides (OATPs) mediate the transmembrane uptake of endogenous compounds and clinically important…
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Highly Cited
2005
Highly Cited
2005
Vectorial Transport of the Peptide CCK-8 by Double-Transfected MDCKII Cells Stably Expressing the Organic Anion Transporter OATP1B3 (OATP8) and the Export Pump ABCC2
K. Letschert
,
M. Komatsu
,
J. Hummel‐Eisenbeiss
,
D. Keppler
Journal of Pharmacology and Experimental…
2005
Corpus ID: 25063238
CCK-8 (l-aspartyl-l-tyrosyl-l-methionylglycyl-l-tryptophyl-l-methionyl-l-aspartyl-l-phenylalaninamide hydrogen sulfate ester), a…
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Highly Cited
2003
Highly Cited
2003
Expression of genes controlling transport and catabolism of prostaglandin E2 in lipopolysaccharide fever.
A. Ivanov
,
A. Scheck
,
A. A. Romanovsky
American Journal of Physiology. Regulatory…
2003
Corpus ID: 1828505
Prostaglandin (PG) E(2) is a principal downstream mediator of fever and other symptoms of systemic inflammation. Its inactivation…
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Highly Cited
2002
Highly Cited
2002
Modulation of monocyte signaling and pore formation in response to agonists of the nucleotide receptor P2X7
M. Aga
,
Christopher J. Johnson
,
+5 authors
B. Darien
Journal of Leukocyte Biology
2002
Corpus ID: 15478520
Previous reports about the nucleotide receptor P2X7, which exhibits ion channel and pore‐forming activity and is known to promote…
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Highly Cited
2001
Highly Cited
2001
Rosuvastatin is a high affinity substrate of hepatic organic anion transporter OATP-C
Colin D. A. Brown
,
A. Windass
,
K. Bleasby
,
B. Lauffart
2001
Corpus ID: 70480366
Highly Cited
2000
Highly Cited
2000
Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter.
Y. Uwai
,
H. Saito
,
K. Inui
European Journal of Pharmacology
2000
Corpus ID: 8203772
Review
1999
Review
1999
Resistance to cisplatin.
S. Akiyama
,
Zhe-Sheng Chen
,
T. Sumizawa
,
T. Furukawa
Anti-Cancer Drug Design
1999
Corpus ID: 31139107
Resistance to cis-diamminedichloroplatinum(II) (cisplatin), a DNA damaging agent, is a major obstacle for its clinical…
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Highly Cited
1998
Highly Cited
1998
Characterization of the Regional Intestinal Kinetics of Drug Efflux in Rat and Human Intestine and in Caco-2 Cells
V. Makhey
,
A. Guo
,
D. Norris
,
P. Hu
,
Jia-chun Yan
,
P. Sinko
Pharmaceutical Research
1998
Corpus ID: 11226595
AbstractPurpose. The aim of the present study was to investigate the transport kinetics of intestinal secretory processes in the…
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