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Organic Anion Transport Polypeptides

Known as: OATP Proteins, SLCO, Organic Anion-Transporting Polypeptide 
A family of transmembrane proteins that play a role in the transport of organic anions including bile acids and bilirubin.
National Institutes of Health

Related topics

Related topics

18 relations
Carrier ProteinsCellular MembraneIntegral Membrane ProteinsIonophore activity

Broader (1)

Organic Anion Transporters

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Differential effect of genetic variants of Na+-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors
The purpose of this study was to investigate the effect of genetic variations in organic anion-transporting polypeptide 1B1… 
Review
2010
Review
2010
Exploring the genetic architecture of neonatal hyperbilirubinemia.
Highly Cited
2008
Highly Cited
2008
Altered expression of organic anion transporter polypeptide (OATP) genes in human breast carcinoma
Organic anion transporter polypeptides (OATPs) mediate the transmembrane uptake of endogenous compounds and clinically important… 
Highly Cited
2005
Highly Cited
2005
Vectorial Transport of the Peptide CCK-8 by Double-Transfected MDCKII Cells Stably Expressing the Organic Anion Transporter OATP1B3 (OATP8) and the Export Pump ABCC2
CCK-8 (l-aspartyl-l-tyrosyl-l-methionylglycyl-l-tryptophyl-l-methionyl-l-aspartyl-l-phenylalaninamide hydrogen sulfate ester), a… 
Highly Cited
2003
Highly Cited
2003
Expression of genes controlling transport and catabolism of prostaglandin E2 in lipopolysaccharide fever.
Prostaglandin (PG) E(2) is a principal downstream mediator of fever and other symptoms of systemic inflammation. Its inactivation… 
Highly Cited
2002
Highly Cited
2002
Modulation of monocyte signaling and pore formation in response to agonists of the nucleotide receptor P2X7
Previous reports about the nucleotide receptor P2X7, which exhibits ion channel and pore‐forming activity and is known to promote… 
Highly Cited
2001
Highly Cited
2001
Rosuvastatin is a high affinity substrate of hepatic organic anion transporter OATP-C
Highly Cited
2000
Highly Cited
2000
Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter.
Review
1999
Review
1999
Resistance to cisplatin.
Resistance to cis-diamminedichloroplatinum(II) (cisplatin), a DNA damaging agent, is a major obstacle for its clinical… 
Highly Cited
1998
Highly Cited
1998
Characterization of the Regional Intestinal Kinetics of Drug Efflux in Rat and Human Intestine and in Caco-2 Cells
AbstractPurpose. The aim of the present study was to investigate the transport kinetics of intestinal secretory processes in the… 
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