FAQ

Organic Anion Transport Polypeptides

Known as: OATP Proteins, SLCO, Organic Anion-Transporting Polypeptide 
A family of transmembrane proteins that play a role in the transport of organic anions including bile acids and bilirubin.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2018
020406019782018

Related topics

Related topics

17 relations
Carrier ProteinsCellular MembraneIntegral Membrane ProteinsIonophore activity
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Broader (1)

Organic Anion Transporters

Related mentions per year

Related mentions per year

1942-2018
19401960198020002020
Organic Anion Transport Polypeptides
Carrier Proteins
Transmembrane Transport
SLCO1B1 gene
Integral Membrane Proteins
Transmembrane Domain

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Interactions of green tea catechins with organic anion-transporting polypeptides.
Organic anion-transporting polypeptides (OATPs) are multispecific transporters that mediate the uptake of numerous drugs and… (More)
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Highly Cited
2005
Highly Cited
2005
Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.
Human organic anion-transporting polypeptide B (OATP-B; OATP2B1) is expressed in the human intestinal epithelial cells, and is… (More)
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Highly Cited
2004
Highly Cited
2004
Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human.
The pH-sensitive activity of human organic anion transporting polypeptide OATP-B, which is expressed at the apical membrane of… (More)
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Highly Cited
2004
Highly Cited
2004
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).
This study aimed to characterize possible relationships between polymorphisms in the drug transporter genes organic anion… (More)
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Highly Cited
2002
Highly Cited
2002
Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter.
Transport of various amphipathic organic compounds is mediated by organic anion transporting polypeptides (OATPs in humans, Oatps… (More)
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Highly Cited
2001
Highly Cited
2001
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver.
BACKGROUND & AIMS Hepatic uptake of cholephilic organic compounds is mediated by members of the organic anion-transporting… (More)
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Highly Cited
2001
Highly Cited
2001
Functional Characterization of Human Organic Anion Transporting Polypeptide B (OATP-B) in Comparison with Liver-Specific OATP-C
Purpose. To assess the functional characteristics of human organic anion transporter B (OATP-B) in comparison with those of the… (More)
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Highly Cited
2000
Highly Cited
2000
A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane.
We cloned and expressed a new organic anion transporting polypeptide (OATP), termed human OATP2, (OATP-C, LST-1; symbol SLC21A6… (More)
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Highly Cited
2000
Highly Cited
2000
Organic anion-transporting polypeptides mediate transport of opioid peptides across blood-brain barrier.
Organic anion-transporting polypeptides (Oatps) are a rapidly growing gene family of polyspecific membrane transporters. In rat… (More)
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Highly Cited
2000
Highly Cited
2000
Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.
We identified three novel transporters structurally belonging to the organic anion transporting polypeptide (OATP) family in… (More)
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