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Organic Anion Transport Polypeptides

Known as: OATP Proteins, SLCO, Organic Anion-Transporting Polypeptide 
A family of transmembrane proteins that play a role in the transport of organic anions including bile acids and bilirubin.
National Institutes of Health

Related topics

Related topics

18 relations
Carrier ProteinsCellular MembraneIntegral Membrane ProteinsIonophore activity

Broader (1)

Organic Anion Transporters

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions
Introduction: Organic anion transporting polypeptide (OATP) uptake transporters are important for the disposition of many drugs… 
Highly Cited
2011
Highly Cited
2011
Differential effect of genetic variants of Na+-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors
The purpose of this study was to investigate the effect of genetic variations in organic anion-transporting polypeptide 1B1… 
2009
2009
P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir
Background Drug efflux (for example, P-glycoprotein [P-gp], multidrug resistance-associated proteins [MRPs] and breast cancer… 
2007
2007
Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells.
Human organic anion transporter 4 (hOAT4) belongs to a family of organic anion transporters that play critical roles in the body… 
Highly Cited
2003
Highly Cited
2003
Expression of genes controlling transport and catabolism of prostaglandin E2 in lipopolysaccharide fever.
Prostaglandin (PG) E(2) is a principal downstream mediator of fever and other symptoms of systemic inflammation. Its inactivation… 
Highly Cited
2002
Highly Cited
2002
Modulation of monocyte signaling and pore formation in response to agonists of the nucleotide receptor P2X7
Previous reports about the nucleotide receptor P2X7, which exhibits ion channel and pore‐forming activity and is known to promote… 
Highly Cited
2001
Highly Cited
2001
Detection of ochratoxin A-induced DNA damage in MDCK cells by alkaline single cell gel electrophoresis (comet assay)
Abstract. The mycotoxin ochratoxin A (OTA), a widespread contaminant of food and feedstuffs, is nephrotoxic, immunosuppressive… 
Highly Cited
2001
Highly Cited
2001
Identification of the Apical Membrane-targeting Signal of the Multidrug Resistance-associated Protein 2 (MRP2/cMOAT)*
The human canalicular multispecific organic anion transporter (cMOAT), known as the multidrug resistance-associated protein 2… 
Highly Cited
1997
Highly Cited
1997
Human canalicular multispecific organic anion transporter (cMOAT) is expressed in human lung, gastric, and colorectal cancer cells.
Human canalicular multispecific organic anion transporter (cMOAT), a glutathione conjugate membrane transporter, has been… 
1982
1982
Effect of organic anions on biliary lipids in the rat.
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