Effect of Deltamethrin on Haematological Indices of Common Carp ( Cyprinus carpio L.)
- Z. Svobodová, V. Lusková, J. Drastichová, M. Svoboda, V. Žlábek
Changes in the erythrocyte profile and plasma total protein after exposure to deltamethrin-based preparation may be referred to possible disruption of haematopoiesis and proteosynthesis.
The effect of diazinon on blood plasma biochemistry in carp (Cyprinus carpio)
- V. Lusková, M. Svoboda, J. Kolářová
The above results of examinations of the biochemical blood plasma profile indicate a marked neurotoxic effect of diazinon in fishes.
THE EFFECT OF DIAZINON ON HAEMATOLOGICAL INDICES OF COMMON CARP (Cyprinus carpio L.)
- M. Svoboda, V. Lusková, J. Drastichová, V. Žlábek
Changes in values of both the erythrocyte and leukocyte profile after exposure to diazinon-based preparation may be refered to disruption of haematopoiesis as well as to a decrease on non-specific immunity of the fish.
Altered expression of organic anion transporter polypeptide (OATP) genes in human breast carcinoma
- Katrin Wlcek, M. Svoboda, F. Sellner, G. Krupitza, W. Jaeger, T. Thalhammer
- BiologyCancer Biology & Therapy
- 1 September 2008
Analysis of the expression pattern of all 11 known OATPs in three breast cancer cell lines using quantitative real-time RT-PCR found that mRNA expression of OATP2B1, OPATP3A1, and OatP4A1 was significantly higher than normal and this was verified in the tissue samples.
Organic anion transporting polypeptides (OATPs): regulation of expression and function.
- M. Svoboda, Juliane Riha, Katrin Wlcek, W. Jaeger, T. Thalhammer
- BiologyCurrent drug metabolism
- 31 January 2011
Changes in the expression of OATPs under pathological conditions will influence transport processes causing an altered accumulation of O ATP substrates in cells of excretory organs and on various blood/organ barriers, which may result in increased toxicity and adverse drug reactions.
Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.
- M. Svoboda, Katrin Wlcek, W. Jäger
- Biology, ChemistryBiomedicine & pharmacotherapy = Biomedecine…
- 1 September 2011
Biochemical Profile of Blood Plasma of Tench ( Tinca tinca L.) During Pre- and Postspawning Period
- M. Svoboda, J. Kouril, B. Vykusova
The blood plasma biochemical profile enabled to assess the state of internal milieu of broodstock during the reproduction period and differences were found in glucose concentration and other biochemical indices between the spawned and unspawned female fish.
Different expression patterns of organic anion transporting polypeptides in osteosarcomas, bone metastases and aneurysmal bone cysts.
- Richard Liedauer, M. Svoboda, T. Thalhammer
- Biology, MedicineOncology Report
- 1 December 2009
High OATP expression levels, particularly in benign bone tumors, suggest an important role of these transporters for providing hormones, their conjugates, prostaglandins and drugs in bone cells and they may influence bone resorption and formation.
B Cells and Ectopic Follicular Structures: Novel Players in Anti-Tumor Programming with Prognostic Power for Patients with Metastatic Colorectal Cancer
- A. Meshcheryakova, D. Tamandl, D. Mechtcheriakova
- Biology, MedicinePLoS ONE
- 6 June 2014
A novel algorithm allowing to assess a link between the local patient-specific immunological capacity and clinical outcome is presented and nominate the magnitude of B lymphocytes, including those organized in ectopic follicles, as novel prognostic marker which is superior to clinicopathological parameters.