FAQ

Organic Anion Transporters

Known as: Membrane Transport Proteins, Organic Anion, Transporters, Organic Anion, Organic Anion Transporters [Chemical/Ingredient] 
Proteins involved in the transport of organic anions. They play an important role in the elimination of a variety of endogenous substances… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2018
024620032018

Related topics

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14 relations
In BloodProcess of secretionadministration & dosageagonists
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Narrower (4)

Organic Anion Transport PolypeptidesOrganic Anion Transport Proteinscitrinurate transporter

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Organic Anion Transporters
physiological aspects
agonists
chemical synthesis
Organic Anion Transport Polypeptides
standards characteristics

Papers overview

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2015
2015
Human organic anion transporter 2 is distinct from organic anion transporters 1 and 3 with respect to transport function.
Phylogentically, organic anion transporter (OAT)1 and OAT3 are closely related, whereas OAT2 is more distant. Experiments with… (More)
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2014
2014
Tenofovir alafenamide is not a substrate for renal organic anion transporters (OATs) and does not exhibit OAT-dependent cytotoxicity.
BACKGROUND Tenofovir alafenamide (TAF) is a novel prodrug of tenofovir that shows enhanced antiretroviral effect and reduced… (More)
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2012
2012
Regulation of renal organic anion and cation transporters by thymoquinone in cisplatin induced kidney injury.
In previous studies, we have demonstrated the biological activity of thymoquinone (TQ), an active compound extracted from the… (More)
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2012
2012
Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8)
Many active components of herbal products are small organic anions, and organic anion transporters were previously demonstrated… (More)
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2011
2011
Critical role of organic anion transporters 1 and 3 in kidney accumulation and toxicity of aristolochic acid I.
Ingestion of aristolochic acid (AA), especially its major constituent aristolochic acid I (AAI), results in severe kidney injury… (More)
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2008
2008
Organic anion transporter 1B1: an important factor in hepatic thyroid hormone and estrogen transport and metabolism.
Sulfation is an important pathway in the metabolism of thyroid hormone and estrogens. Sulfation of estrogens is reversible by… (More)
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2008
2008
Analysis of regulatory polymorphisms in organic ion transporter genes (SLC22A) in the kidney
AbstractOrganic cation transporters (OCTs) and organic anion transporters (OATs) (SLC22A family) play crucial roles in the renal… (More)
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2005
2005
Interactions of Stevioside and Steviol with Renal Organic Anion Transporters in S2 Cells and Mouse Renal Cortical Slices
Our previous studies have shown that both stevioside and steviol inhibited transepithelial transport of para-aminohippurate (PAH… (More)
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2004
2004
Expression Levels of Renal Organic Anion Transporters (OATs) and Their Correlation with Anionic Drug Excretion in Patients with Renal Diseases
Purpose. Because the urinary excretion of drugs is often decreased in renal diseases, dosage regimens are adjusted to avoid… (More)
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2003
2003
Detection of the Human Organic Anion Transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in Liver and Hepatocellular Carcinoma
Transport proteins mediating the selective uptake of organic anions into human hepatocytes include the organic anion transporters… (More)
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