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Organic Anion Transporters

Known as: Membrane Transport Proteins, Organic Anion, Transporters, Organic Anion, Organic Anion Transporters [Chemical/Ingredient] 
Proteins involved in the transport of organic anions. They play an important role in the elimination of a variety of endogenous substances… Expand
National Institutes of Health

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28 relations

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BaiG protein, Clostridium scindensBenk protein, Acinetobacter calcoaceticusCitT protein, E coliHcaT protein, E coli
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In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

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Review
2013
Review
2013
The SLC22 family with transporters of organic cations, anions and zwitterions.
The SLC22 family contains 13 functionally characterized human plasma membrane proteins each with 12 predicted α-helical… Expand
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Review
2012
Review
2012
Drug transport by Organic Anion Transporters (OATs).
Common to all so far functionally characterized Organic Anion Transporters (OATs) is their broad substrate specificity and their… Expand
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Highly Cited
2011
Highly Cited
2011
Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors.
We have obtained, for the first time, a quantitative protein expression profile of membrane transporters and receptors in human… Expand
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Review
2004
Review
2004
The SLC22 drug transporter family
The SLC22 family comprises organic cation transporters (OCTs), zwitterion/cation transporters (OCTNs), and organic anion… Expand
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Highly Cited
2003
Highly Cited
2003
Involvement of Human Organic Anion Transporting Polypeptide OATP-B (SLC21A9) in pH-Dependent Transport across Intestinal Apical Membrane
Some organic anions are absorbed from the gastrointestinal tract through carrier-mediated transport mechanism(s), which may… Expand
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Highly Cited
2003
Highly Cited
2003
Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis.
Hepatobiliary transporters are down-regulated in toxic and cholestatic liver injury. Cytokines such as tumor necrosis factor… Expand
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Highly Cited
2002
Highly Cited
2002
Characterization of Methotrexate Transport and Its Drug Interactions with Human Organic Anion Transporters
Life-threatening drug interactions are known to occur between methotrexate and nonsteroidal anti-inflammatory drugs (NSAIDs… Expand
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Highly Cited
2002
Highly Cited
2002
Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity.
In uremic patients, various uremic toxins are accumulated and exert various biologic effects on uremia. Indoxyl sulfate (IS) is… Expand
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Highly Cited
2002
Highly Cited
2002
Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.
The organic anion transport system is involved in the tubular excretion and reabsorption of various drugs and substances. The… Expand
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Review
2000
Review
2000
A family of drug transporters: the multidrug resistance-associated proteins.
The human multidrug resistance-associated protein (MRP) family currently has seven members. The ability of several of these… Expand
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