ORC1L protein, human

Known as: Origin Recognition Complex Subunit 1-Like, Origin Recognition Complex Subunit 1, origin recognition complex, subunit 1, human 
Origin recognition complex subunit 1 (861 aa, ~97 kDa) is encoded by the human ORC1 gene. This protein plays a role in DNA replication.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2016
012319932016

Papers overview

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2016
2016
Newly born cells either continue to proliferate or exit the cell division cycle. This decision involves delaying expression of… (More)
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2013
2013
We report the genome-wide mapping of ORC1 binding sites in mammals, by chromatin immunoprecipitation and parallel sequencing… (More)
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Highly Cited
2012
Highly Cited
2012
The recognition of distinctly modified histones by specialized ‘effector’ proteins constitutes a key mechanism for transducing… (More)
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2011
Highly Cited
2011
Studies into disorders of extreme growth failure (for example, Seckel syndrome and Majewski osteodysplastic primordial dwarfism… (More)
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2008
2008
Telomeres have the capacity to recruit proteins that facilitate the spreading of heterochromatin into subtelomeric DNA regions… (More)
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2006
2006
Previous studies have suggested that the activity of the mammalian origin recognition complex (ORC) is regulated by cell-cycle… (More)
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2006
2006
In higher eukaryotes, the origin recognition complex (ORC) lacks sequence-specific DNA binding, and it remains unclear what other… (More)
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2005
2005
In the present paper a simple, yet ingenious and accurate structural approach towards pattern recognition has been proposed… (More)
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2003
2003
Two isoforms of the human ornithine carrier, ORC1 and ORC2, have been identified by overexpression of the proteins in bacteria… (More)
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2002
2002
Previous studies have shown that changes in the affinity of the hamster Orc1 protein for chromatin during the M-to-G(1… (More)
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