OPRM1 gene

Known as: MOR, OPRM, OPIOID RECEPTOR, MU-1 
This gene plays a role in opioid-dependent G protein-coupled receptor signaling.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
This study investigated whether automatic approach action tendencies for alcohol-related stimuli were associated with variation… (More)
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Highly Cited
2009
Highly Cited
2009
Scientific understanding of social pain--the hurt feelings resulting from social rejection, separation, or loss--has been… (More)
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Highly Cited
2008
Highly Cited
2008
The pharmacokinetics and pharmacodynamics of morphine are under the control of several polymorphic genes, which can account for… (More)
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Highly Cited
2008
Highly Cited
2008
In a variety of species, development of attachment to a caregiver is crucial for infant survival and partly mediated by the… (More)
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Highly Cited
2008
Highly Cited
2008
CONTEXT Naltrexone hydrochloride treatment for alcohol dependence works for some individuals but not for everyone. Asn40Asp, a… (More)
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Highly Cited
2007
Highly Cited
2007
Pain is a complex human trait. It is likely that the interaction of multiple genes, each with a small individual effect, along… (More)
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Highly Cited
2006
Highly Cited
2006
We examined 13 single nucleotide polymorphisms (SNPs) spanning the coding region of the mu-opioid receptor gene (OPRM1), among… (More)
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Highly Cited
2005
Highly Cited
2005
Responses to painful stimuli are characterized by tremendous interindividual variability, and genetic factors likely account for… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Recent research has implicated the endogenous opioid system in the development of alcohol use disorders. The A118G… (More)
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Highly Cited
1999
Highly Cited
1999
The ability of morphine to alleviate pain is mediated through a heterotrimeric guanine nucleotide binding protein (G protein… (More)
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