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Mitochondria has an essential role in myocardial tissue homeostasis; thus deterioration in mitochondrial function eventually… Expand Multiple sclerosis (MS) is a chronic inflammatory autoimmune demyelinating disease of the central nervous system. It affects… Expand Objective: The chemotherapeutic agent mitoxantrone was approved for use in multiple sclerosis (MS) in 2000. After a review of all… Expand Mitoxantrone is the first drug approved for the treatment of secondary progressive multiple sclerosis (SPMS) in the United States… Expand Understanding of the etiology and pathogenesis of MS has improved significantly in recent years. In addition, important… Expand Background Mitoxantrone (MITO) is associated with dose-related cardiotoxicity when administered concomitantly with other… Expand BACKGROUND AND OBJECTIVES
The objective of improving the quality of responses of chronic lymphocytic leukemia (CLL) patients has… Expand Due to the close homology between bacterial and tumor cell transporter proteins, some antiplasmid and anticancer compounds were… Expand The novel antineoplastic drug mitoxantrone was studied for its genotoxic effects in Drosophila melanogaster. In male germ cells… Expand Exposure of L1210 cells to DNA-intercalating antitumor drugs Novantrone (mitoxantrone; 20 ng/ml), doxorubicin (0.5 micrograms/ml… Expand