Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Mitoxantrone

Known as: 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthroquinone, 1,4-DIHYDROXY-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-anthracenedione, Mitoxantronum 
An anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
BACKGROUND Cabazitaxel is a novel tubulin-binding taxane drug with antitumour activity in docetaxel-resistant cancers. We aimed… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
PURPOSE The TAX 327 study compared docetaxel administered every 3 weeks (D3), weekly docetaxel (D1), and mitoxantrone (M), each… Expand
  • figure 1
  • table 1
  • figure 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
BACKGROUND Mitoxantrone plus prednisone reduces pain and improves the quality of life in men with advanced, hormone-refractory… Expand
  • table 1
  • table 2
  • figure 1
  • table 3
  • table 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
BACKGROUND Mitoxantrone-based chemotherapy palliates pain without extending survival in men with progressive androgen-independent… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
A subset of stem cells, termed the "side population" (SP), has been identified in several tissues in mammalian species. These… Expand
  • table 1
  • figure 2
  • figure 4
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND Treatment options for patients with secondary progressive multiple sclerosis are few. Encouraging results in open… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Reports of multiple distinct mitoxantrone-resistant sublines without overexpression of P-glycoprotein or the multidrug-resistance… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
Highly Cited
1999
Highly Cited
1999
PURPOSE Approximately 40,000 men die each year of hormone-refractory prostate cancer (HRPC). The results of treatment with… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
MCF-7/AdrVp is a multidrug-resistant human breast cancer subline that displays an ATP-dependent reduction in the intracellular… Expand
Is this relevant?
Highly Cited
1996
Highly Cited
1996
PURPOSE To investigate the benefit of chemotherapy in patients with symptomatic hormone-resistant prostate cancer using relevant… Expand
Is this relevant?