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Mitoxantrone Hydrochloride

Known as: 1,3-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthracenedione Dihydrochloride, Mitoxantrone Dihydrochloride, Mitozantrone Hydrochloride 
The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby… 
National Institutes of Health

Related topics

Related topics

38 relations

Narrower (4)

CL 232315NSC-301739NovantroneOnkotrone
CNOP RegimenCongestive heart failureEtoposide/Ifosfamide/Mesna/MitoxantroneFMC protocol

Broader (1)

Mitoxantrone

Papers overview

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2011
2011
Increased virulence of Candida albicans after antineoplastic chemotherapy
Although yeasts of the genus Candida are part of the normal human oral microbiota, in cancer patients they may be associated with… 
2011
2011
Изучение влияния препаратов антиоксидантного действия на физиологические реакции животных, получающих противоопухолевую химиотерапию
The present study aimed to investigate the influence of combination of the synthetic antioxidant mexidol (3-oxy-6-metyl-2-etyl… 
2011
2011
Security evaluation of mitoxantrone hydrochloride and sodium chloride injection
Objective To study the security of mitoxantrone hydrochloride and sodium chloride injection.Method Carrying out sensitivity test… 
2008
2008
Assay of ephedrina hydrochloridum and pseudoephedrine hydrochloride in Chuanliting Spray by HPLC
AIM: To establish a RP-HPLC method for determining ephedrina hydrochloridum and pseudoephedrine hydrochloride in Chuanliting… 
2006
2006
Determination of mitoxantrone hydrochloride based on KMnO_4-HCHO reaction by flow injection chemiluminescence analysis
Objective: To establish a novel flow injection chemiluminescence ( FI-CL) system for determination of mitoxantrone hydrochloride… 
2002
2002
Gateways to Clinical Trials: July-August 2002
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
2000
2000
Flow Injection Chemiluminescence Determination of Cytarabini Hydrochloridum with On-line Electrogenerated Hypochlorite
A novel flow injection chemiluminescence method for the determination of cytarabini hydrochloridum based on its inhibition of… 
1996
1996
Does induction chemotherapy with a mitoxantrone/vinorelbine regimen allow a breast-conservative treatment in patients with operable locoregional breast cancer?
BackgroundIn recent years, induction chemotherapy has been tested by several investigators in the management of operable breast… 
1992
1992
[Electron microscopic studies on the effects of irradiation and mitoxantrone hydrochloride (Novantrone), alone and in combination, on cells of Harding-Passey melanoma in monolayer culture].
2 Gy or 4 Gy irradiation of cultured Harding-Passey melanoma cells revealed electronmicroscopically none or little cell damage… 
1980
1980
[Mitoxantrone HCl (1,4-dihydroxy-4, 8-bis[[2-(hydroxyethyl)-amino-ethyl)]amino 9,10-anthracenedione dihydrochloride (NSC 301739) - a new cytostatic].