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Mitoxantrone Hydrochloride

Known as: 1,3-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthracenedione Dihydrochloride, Mitoxantrone Dihydrochloride, Mitozantrone Hydrochloride 
The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby… 
National Institutes of Health

Related topics

Related topics

38 relations

Narrower (4)

CL 232315NSC-301739NovantroneOnkotrone
CNOP RegimenCongestive heart failureEtoposide/Ifosfamide/Mesna/MitoxantroneFMC protocol

Broader (1)

Mitoxantrone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Initial biopsy Gleason score as a predictive marker for survival benefit in patients with castration-resistant prostate cancer treated with docetaxel: data from the TAX327 study.
Highly Cited
2011
Highly Cited
2011
Cytarabine dose for acute myeloid leukemia.
BACKGROUND Cytarabine (ara-C) is an important drug in the treatment of acute myeloid leukemia (AML). High-dose cytarabine (2000… 
Highly Cited
2011
Highly Cited
2011
Cytarabine dose for acute myeloid leukemia.
  • M. Mathisen
  • The New England journal of medicine
  • 2011
  • Corpus ID: 6752180
The authors reply: Shukla correctly notes that smokeless tobacco use is common among Indians and Bangladeshis. Because habitual… 
Highly Cited
2006
Highly Cited
2006
Study of mitoxantrone for the treatment of recurrent neuromyelitis optica (Devic disease).
BACKGROUND Neuromyelitis optica is a severe demyelinating disease that selectively involves the optic nerves and the spinal cord… 
Review
2006
Review
2006
Fertility in patients with multiple sclerosis: current knowledge and future perspectives
The issue of fertility in patients with multiple sclerosis (MS) has not been exhaustively studied. Epidemiological data have… 
Highly Cited
2001
Highly Cited
2001
Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial.
In an attempt to improve induction chemotherapy for older patients with acute myeloid leukemia (AML),1314 patients were… 
Highly Cited
2000
Highly Cited
2000
Safety of fludarabine, mitoxantrone, and dexamethasone combined with rituximab in the treatment of stage IV indolent lymphoma.
Rituximab (Rituxan; Genentech, Inc, South San Francisco, CA and IDEC Pharmaceutical Corporation, San Diego, CA) is an effective… 
Highly Cited
1999
Highly Cited
1999
Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells.
The mitoxantrone resistance (MXR) gene encodes a recently characterized ATP-binding cassette half-transporter that confers… 
1997
1997
Fludarabine-mitoxantrone combination-containing regimen in recurrent low-grade non-Hodgkin's lymphoma.
BACKGROUND The promising results of fludarabine (FLU) in chronic lymphocytic leukemia have prompted its extensive evaluation in… 
Highly Cited
1986
Highly Cited
1986
Selective immunomodulation by the antineoplastic agent mitoxantrone. I. Suppression of B lymphocyte function.
Novantrone mitoxantrone, an antineoplastic agent with antiproliferative properties, is under investigation as an immunomodulating… 
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