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Mitoxantrone Hydrochloride
Known as:
1,3-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthracenedione Dihydrochloride
, Mitoxantrone Dihydrochloride
, Mitozantrone Hydrochloride
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The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby…
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National Institutes of Health
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Related topics
Related topics
38 relations
Narrower (4)
CL 232315
NSC-301739
Novantrone
Onkotrone
CNOP Regimen
Congestive heart failure
Etoposide/Ifosfamide/Mesna/Mitoxantrone
FMC protocol
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Broader (1)
Mitoxantrone
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Initial biopsy Gleason score as a predictive marker for survival benefit in patients with castration-resistant prostate cancer treated with docetaxel: data from the TAX327 study.
R. V. van Soest
,
E. D. de Morrée
,
Liji Shen
,
I. Tannock
,
M. Eisenberger
,
R. de Wit
European urology
2014
Corpus ID: 27239611
Highly Cited
2011
Highly Cited
2011
Cytarabine dose for acute myeloid leukemia.
B. Löwenberg
,
T. Pabst
,
+15 authors
G. Ossenkoppele
The New England journal of medicine
2011
Corpus ID: 205092711
BACKGROUND Cytarabine (ara-C) is an important drug in the treatment of acute myeloid leukemia (AML). High-dose cytarabine (2000…
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Highly Cited
2011
Highly Cited
2011
Cytarabine dose for acute myeloid leukemia.
M. Mathisen
The New England journal of medicine
2011
Corpus ID: 6752180
The authors reply: Shukla correctly notes that smokeless tobacco use is common among Indians and Bangladeshis. Because habitual…
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Highly Cited
2006
Highly Cited
2006
Study of mitoxantrone for the treatment of recurrent neuromyelitis optica (Devic disease).
B. Weinstock-Guttman
,
M. Ramanathan
,
+4 authors
R. Bakshi
Archives of neurology
2006
Corpus ID: 24123362
BACKGROUND Neuromyelitis optica is a severe demyelinating disease that selectively involves the optic nerves and the spinal cord…
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Review
2006
Review
2006
Fertility in patients with multiple sclerosis: current knowledge and future perspectives
P. Cavalla
,
V. Rovei
,
+4 authors
A. Revelli
Neurological Sciences
2006
Corpus ID: 24259311
The issue of fertility in patients with multiple sclerosis (MS) has not been exhaustively studied. Epidemiological data have…
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Highly Cited
2001
Highly Cited
2001
Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial.
A. Goldstone
,
A. Burnett
,
K. Wheatley
,
A. Smith
,
R. Hutchinson
,
R. Clark
Blood
2001
Corpus ID: 1028772
In an attempt to improve induction chemotherapy for older patients with acute myeloid leukemia (AML),1314 patients were…
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Highly Cited
2000
Highly Cited
2000
Safety of fludarabine, mitoxantrone, and dexamethasone combined with rituximab in the treatment of stage IV indolent lymphoma.
P. Mclaughlin
,
F. Hagemeister
,
+9 authors
F. Cabanillas
Seminars in oncology
2000
Corpus ID: 30347166
Rituximab (Rituxan; Genentech, Inc, South San Francisco, CA and IDEC Pharmaceutical Corporation, San Diego, CA) is an effective…
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Highly Cited
1999
Highly Cited
1999
Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells.
M. Brangi
,
T. Litman
,
+7 authors
S. Bates
Cancer research
1999
Corpus ID: 37621241
The mitoxantrone resistance (MXR) gene encodes a recently characterized ATP-binding cassette half-transporter that confers…
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1997
1997
Fludarabine-mitoxantrone combination-containing regimen in recurrent low-grade non-Hodgkin's lymphoma.
P. Zinzani
,
M. Bendandi
,
M. Magagnoli
,
F. Gherlinzoni
,
E. Merla
,
S. Tura
Annals of oncology : official journal of the…
1997
Corpus ID: 10170366
BACKGROUND The promising results of fludarabine (FLU) in chronic lymphocytic leukemia have prompted its extensive evaluation in…
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Highly Cited
1986
Highly Cited
1986
Selective immunomodulation by the antineoplastic agent mitoxantrone. I. Suppression of B lymphocyte function.
J. Fidler
,
S. Dejoy
,
J. Gibbons
Journal of immunology
1986
Corpus ID: 26890667
Novantrone mitoxantrone, an antineoplastic agent with antiproliferative properties, is under investigation as an immunomodulating…
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