Mitoxantrone Hydrochloride

Known as: 1,3-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthracenedione Dihydrochloride, Mitoxantrone Dihydrochloride, Mitozantrone Hydrochloride 
The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby… (More)
National Institutes of Health

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35 relations

Narrower (4)

CL 232315NSC-301739NovantroneOnkotrone
CNOP RegimenCongestive heart failureEtoposide/Ifosfamide/Mesna/MitoxantroneFMC protocol
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Broader (1)

Mitoxantrone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Initial biopsy Gleason score as a predictive marker for survival benefit in patients with castration-resistant prostate cancer treated with docetaxel: data from the TAX327 study.
BACKGROUND Since 2004, docetaxel has been the standard first-line systemic therapy for patients with metastatic castration… (More)
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2012
2012
Novel nanostructured lipid-dextran sulfate hybrid carriers overcome tumor multidrug resistance of mitoxantrone hydrochloride.
UNLABELLED Novel nanostructured lipid-dextran sulfate hybrid carriers (NLDCs) were successfully developed for sustained delivery… (More)
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Highly Cited
2011
Highly Cited
2011
Cytarabine dose for acute myeloid leukemia.
BACKGROUND Cytarabine (ara-C) is an important drug in the treatment of acute myeloid leukemia (AML). High-dose cytarabine (2000… (More)
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2009
2009
Multidrug Resistance Protein ( P-Glycoprotein ; MDR 1 )
 
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Highly Cited
2006
Highly Cited
2006
Study of mitoxantrone for the treatment of recurrent neuromyelitis optica (Devic disease).
BACKGROUND Neuromyelitis optica is a severe demyelinating disease that selectively involves the optic nerves and the spinal cord… (More)
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Highly Cited
2001
Highly Cited
2001
Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial.
In an attempt to improve induction chemotherapy for older patients with acute myeloid leukemia (AML),1314 patients were… (More)
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1996
1996
In vitro resistance to cytosine arabinoside, not to daunorubicin, is associated with the risk of relapse in de novo acute myeloid leukaemia.
The efficacy of chemotherapy in acute myeloid leukaemia (AML) is limited by clinical drug resistance. We determined in vitro… (More)
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1996
1996
Prednimustine, mitoxantrone (PmM) vs cyclophosphamide, vincristine, prednisone (COP) for the treatment of advanced low-grade non-Hodgkin's lymphoma. German Low-Grade Lymphoma Study Group.
The current study was initiated to compare the anti-lymphoma activity and side-effects of prednimustine/mitoxantrone (PmM) vs… (More)
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1986
1986
Selective immunomodulation by the antineoplastic agent mitoxantrone. I. Suppression of B lymphocyte function.
Novantrone mitoxantrone, an antineoplastic agent with antiproliferative properties, is under investigation as an immunomodulating… (More)
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1983
1983
Mitoxantrone hydrochloride (NSC-310739) in lymphoma
The members of the Southwest Oncology Group have treated thirteen patients with Hodgkin's disease and thirty-seven with non… (More)
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