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Mitoxantrone Hydrochloride

Known as: 1,3-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthracenedione Dihydrochloride, Mitoxantrone Dihydrochloride, Mitozantrone Hydrochloride 
The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Since 2004, docetaxel has been the standard first-line systemic therapy for patients with metastatic castration… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Cytarabine (ara-C) is an important drug in the treatment of acute myeloid leukemia (AML). High-dose cytarabine (2000… Expand
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Highly Cited
2011
Highly Cited
2011
The authors reply: Shukla correctly notes that smokeless tobacco use is common among Indians and Bangladeshis. Because habitual… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Neuromyelitis optica is a severe demyelinating disease that selectively involves the optic nerves and the spinal cord… Expand
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Highly Cited
2001
Highly Cited
2001
In an attempt to improve induction chemotherapy for older patients with acute myeloid leukemia (AML),1314 patients were… Expand
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Highly Cited
2000
Highly Cited
2000
Rituximab (Rituxan; Genentech, Inc, South San Francisco, CA and IDEC Pharmaceutical Corporation, San Diego, CA) is an effective… Expand
Highly Cited
1999
Highly Cited
1999
The mitoxantrone resistance (MXR) gene encodes a recently characterized ATP-binding cassette half-transporter that confers… Expand
Highly Cited
1996
Highly Cited
1996
The current study was initiated to compare the anti-lymphoma activity and side-effects of prednimustine/mitoxantrone (PmM) vs… Expand
Highly Cited
1986
Highly Cited
1986
Novantrone mitoxantrone, an antineoplastic agent with antiproliferative properties, is under investigation as an immunomodulating… Expand
Highly Cited
1983
Highly Cited
1983
Twenty-six patients with acute leukemia in relapse were treated with mitoxantrone (dihydroxyanthracenedione dihydrochloride). The… Expand
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