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Nifedipine

Known as: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester, Nifedipino, Nifedipinum 
A dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and… 
National Institutes of Health

Related topics

Related topics

42 relations
24 HR Nifedipine 30 MG Extended Release Oral Tablet24 HR Nifedipine 30 MG Extended Release Oral Tablet [Adalat]24 HR Nifedipine 60 MG Extended Release Oral Tablet [Afeditab CR]Atenolol / Nifedipine

Narrower (20)

AdalatAdapineAntrolinBAY-a-1040

Broader (5)

AminopyrineCalcium Channel BlockersTocolytic AgentsVasodilator Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Verapamil and nifedipine inhibition of contractions induced by potassium and noradrenaline in human mesenteric arteries and veins.
Ring preparations of human mesenteric arteries and veins were contracted by noradrenaline (1.8 x 10(-5)M) or potassium (127mM… 
Highly Cited
1996
Highly Cited
1996
Peripheral edema due to nifedipine-itraconazole interaction: a case report.
We report a case of a drug interaction observed in a patient who was administered itraconazole for pedal onychomycosis and whose… 
Highly Cited
1984
Highly Cited
1984
No Effect of Nifedipine on Atherogenesis in Cholesterol‐Fed Rabbits
It was recently reported that the calcium antagonist nifedipine suppresses aortic cholesterol accumulation in cholesterol-fed… 
Highly Cited
1984
Highly Cited
1984
Beneficial effects of nifedipine on rest and exercise myocardial energetics in patients with congestive heart failure.
Rest and exercise systemic hemodynamic parameters, coronary blood flow, and myocardial energetics were assessed before and 15 min… 
Highly Cited
1983
Highly Cited
1983
Measurement of nifedipine in plasma by gas--liquid chromatography and electron-capture detection.
In this method for measuring nifedipine, a calcium-channel inhibitor now widely used in the treatment of cardiovascular disease… 
Highly Cited
1983
Highly Cited
1983
Comparison of the antianginal effectiveness of nifedipine, verapamil, and isosorbide dinitrate in patients receiving propranolol: a double-blind study.
Ten men with stable angina not fully relieved by optimal doses of propranolol were given on each of four mornings a single dose… 
Highly Cited
1982
Highly Cited
1982
Inhibition of bronchoconstriction in the guinea pig by a calcium channel blocker, nifedipine.
We investigated the inhibitory effects of nifedipine, a calcium channel blocker, on airway smooth muscle constriction in the… 
Highly Cited
1981
Highly Cited
1981
Efficacy of nifedipine in rest angina refractory to propranolol and nitrates in patients with obstructive coronary artery disease.
Nineteen patients with recurrent rest angina were given oral nifedipine. All patients had chest discomfort refractory to… 
Highly Cited
1980
Highly Cited
1980
Crystal structures of calcium channel antagonists: 2,6-dimethyl-3,5-dicarbomethoxy-4-[2-nitro-, 3-cyano-, 4-(dimethylamino)-, and 2,3,4,5,6-pentafluorophenyl]-1,4-dihydropyridine.
The crystal structures of 2,6-dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine (Nifedipine) and the 3-cyano-, 4… 
Highly Cited
1980
Highly Cited
1980
Improved performance of ischemic canine myocardium in response to nifedipine and diltiazem.
To characterize the effects of Ca2+ antagonists on the performance of the ischemic myocardium, we administered nifedipine and…