Nifedipine

Known as: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester, Nifedipino, Nifedipinum 
A dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
BACKGROUND Calcium antagonists are widely prescribed for angina pectoris but their effect on clinical outcome is controversial… (More)
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Highly Cited
2003
Highly Cited
2003
Midazolam, triazolam (TRZ), testosterone, and nifedipine have all been widely used as probes for in vitro metabolism of CYP3A. We… (More)
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Review
2003
Review
2003
OBJECTIVE To attempt to determine the relative value of preclinical cardiac electrophysiology data (in vitro and in vivo) for… (More)
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Highly Cited
2002
Highly Cited
2002
The purpose of this study is to characterize the nature and solid-state properties of a solid dispersion system of nifedipine (33… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The efficacy of antihypertensive drugs newer than diuretics and beta-blockers has not been established. We compared… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND Exaggerated pulmonary-artery pressure due to hypoxic vasoconstriction is considered an important pathogenetic factor… (More)
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Highly Cited
1990
Highly Cited
1990
425 patients showing mild coronary artery disease (CAD) on arteriography were enrolled in a multicentre trial and randomised to… (More)
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Highly Cited
1986
Highly Cited
1986
The metabolism of the dihydropyridine calcium antagonist and vasodilator nifedipine has been reported to exhibit polymorphism… (More)
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Highly Cited
1981
Highly Cited
1981
We tested the effects of nifedipine, a calcium antagonist, on atherogenesis in rabbits fed a 2% cholesterol diet. The drug was… (More)
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Review
1980
Review
1980
Calcium antagonists (slow channel blocking agents) are a very heterogeneous group of agents with dissimilar structural… (More)
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