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Aminopyrine

Known as: Amidophenazon, 3-Keto-1,5-dimethyl-4-dimethylamino-2-phenyl-2,3-dihydropyrazole, 1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazolone 
A pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of AGRANULOCYTOSIS. A breath test with 13C-labeled… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (29)

4-formylaminoantipyrineBR-4935DipyroneEufibron
Aminopyrine:MCnc:Pt:Exhl gas:QnAminopyrine:MCnc:Pt:Ser/Plas:QnAminopyrine:Mass:Pt:Dose:QnIn Blood

Broader (1)

pyridine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Comparative expression of liver cytochrome P450-dependent monooxygenases in the horse and in other agricultural and laboratory species.
Highly Cited
1988
Highly Cited
1988
Depression by morphine and the non-opioid analgesic agents, metamizol (dipyrone), lysine acetylsalicylate, and paracetamol, of activity in rat thalamus neurones evoked by electrical stimulation of…
Highly Cited
1987
Highly Cited
1987
Inhibition of gastric H+,K+-ATPase and acid secretion by SCH 28080, a substituted pyridyl(1,2a)imidazole.
Highly Cited
1980
Highly Cited
1980
The effect of cimetidine on in vitro and in vivo microsomal drug metabolism in the rat.
Highly Cited
1976
Highly Cited
1976
Effect of growth hormone release-inhibiting hormone on gastric secretion, mucosal blood flow, and serum gastrin.
Highly Cited
1975
Highly Cited
1975
Studies on the disposition of antipyrine, aminopyrine, and phenacetin using plasma, saliva, and urine
In normal male subjects, the half‐lives of antipyrine, aminopyrine, or phenacetin were not significantly different from the half… 
Highly Cited
1973
Highly Cited
1973
Interaction of mixed-function oxidation with biosynthetic processes. 1. Inhibition of gluconeogenesis by aminopyrine in perfused rat liver.
Gluconeogenesis from lactate was studied in perfused livers from phenobarbital-pretreated rats fasted for 24 h. Maximal rates of… 
Highly Cited
1972
Highly Cited
1972
Central monoamines and antinociceptive drug action.
Highly Cited
1965
Highly Cited
1965
Liver response tests. 3. Liver enlargement and stimulation of microsomal processing enzyme activity.
Highly Cited
1950
Highly Cited
1950
The fate of aminopyrine (pyramidon) in man and methods for the estimation of aminopyrine and its metabolites in biological material.
Methods are described for the estimation of Pyramidon and two of its metabolites, 4-aminoantipyrine and N-acetyl 4… 
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