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Dipyrone

Known as: Methanesulfonic acid, ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino)-, sodium salt, Metamizol, Metamizole 
A drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Policy Points: Our study indicates that there are opportunities for cost savings in generic drug markets in Europe and the United… Expand
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Highly Cited
2007
Highly Cited
2007
Dipyrone is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX). In contrast to classical COX… Expand
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Highly Cited
2004
Highly Cited
2004
Medicinal drugs were found to be ubiquitous in the river Elbe, its tributary the river Saale and in other tributaries at their… Expand
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Highly Cited
2004
Highly Cited
2004
ObjectivesReported estimates of the risk of agranulocytosis associated with metamizol have varied by several orders of magnitude… Expand
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Highly Cited
2003
Highly Cited
2003
The aim of this study is to examine possible antioxidant and analgesic activities of turpentine exudes from Pinus nigra Arn… Expand
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Highly Cited
2002
Highly Cited
2002
Two cyclooxygenase isozymes, COX-1 and -2, are known to catalyze the rate-limiting step of prostaglandin synthesis and are the… Expand
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Highly Cited
2002
Highly Cited
2002
We evaluated the effect of several K(+) channel blockers on the peripheral antinociception induced by dipyrone using the rat paw… Expand
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Highly Cited
2001
Highly Cited
2001
&NA; Individual differences in pharmacokinetics and pharmacodynamics, the type of pain and the method of drug administration can… Expand
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Highly Cited
2000
Highly Cited
2000
Many different systems for the assessment of pain in newborns and infants have been tested for validity, rarely for reliability… Expand
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Review
1995
Review
1995
SummaryThe pharmacokinetics of dipyrone are characterised by rapid hydrolysis to the active moiety 4-methyl-amino-antipyrine (MAA… Expand
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