Semantic Scholar uses AI to extract papers important to this topic.
Recently, a subset of neurons was identified in the arcuate nucleus of the hypothalamus that colocalize three neuropeptides… Expand Kisspeptin is encoded by the Kiss1 gene, and kisspeptin signaling plays a critical role in reproduction. In rodents, kisspeptin… Expand The timely secretion of gonadal sex steroids is essential for the initiation of puberty, the postpubertal maintenance of… Expand Kisspeptin is a potent stimulator of GnRH secretion that has been implicated in the feedback actions of ovarian steroids. In ewes… Expand Aprepitant is a novel neurokinin 1 (NK1) antagonist that has been shown to improve control of chemotherapy‐induced nausea and… Expand PURPOSE
In early clinical trials with patients receiving highly emetogenic chemotherapy, the neurokinin antagonist aprepitant… Expand Inflammation, trauma, or nerve injury may cause enduring hyperalgesia, an enhanced sensitivity to painful stimuli. Neurons in… Expand SR 48968 is a potent and selective non-peptide antagonist of the neurokinin A (NK2) receptor. SR 48968 selectively inhibited… Expand Synthetic oligonucleotides were used to screen a rat striatal cDNA library for sequences corresponding to the tachykinin peptides… Expand The neuropeptide receptors which are present in very small quantities in the cell and are embedded tightly in the plasma membrane… Expand