P. Holzer

Publications441
h-index71
Citations20,499
Highly Influential Citations630
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  • Publications
  • Influence
Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons.
  • P. Holzer
  • Chemistry, Medicine
  • Pharmacological reviews
  • 1 June 1991
Local effector functions of capsaicin-sensitive sensory nerve endings: Involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides
  • P. Holzer
  • Medicine, Chemistry
  • Neuroscience
  • 1 March 1988
Etude du mecanisme d'action des neurones sensoriels et des fonctions de leurs effecteurs locaux en reponse a differents stimuli, au niveau des tissus directement en contact avec l'environnement… Expand
Neurogenic vasodilatation and plasma leakage in the skin.
  • P. Holzer
  • Chemistry, Medicine
  • General pharmacology
  • 1998
TLDR
CGRP, SP, and NKA receptor antagonists are powerful pharmacological tools to inhibit neurogenic inflammation at the postjunctional level and have a bearing on chronic inflammatory disease. Expand
Neural emergency system in the stomach.
  • P. Holzer
  • Medicine
  • Gastroenterology
  • 1 April 1998
TLDR
The pathophysiological potential of the neural emergency system is best portrayed by the gastric hyperemic response to acid backdiffusion, which is signaled by afferent nerve fibers and creates favorable conditions for rapid restitution and healing of the wounded mucosa. Expand
Acid-sensitive ion channels and receptors.
  • P. Holzer
  • Chemistry, Medicine
  • Handbook of experimental pharmacology
  • 2009
TLDR
Emerging evidence indicates that many of the acid-sensitive ion channels and receptors play a role in acid sensing, acid-induced pain and acid-evoked feedback regulation of homeostatic reactions, and that acid-base regulation is a vital issue for cell and tissue homeostasis. Expand
Neuropeptide Y, peptide YY and pancreatic polypeptide in the gut–brain axis
TLDR
The findings underscore the important role of the NPY-Y receptor system at several levels of the gut–brain axis in which NPY, PYY and PP operate both as neural and endocrine messengers. Expand
Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication
Emerging evidence indicates that disruption of the gut microbial community (dysbiosis) impairs mental health. Germ-free mice and antibiotic-induced gut dysbiosis are two approaches to establish… Expand
Tachykinins in the gut. Part I. Expression, release and motor function.
TLDR
It would seem conceivable, therefore, that tachykinin agonists and antagonists are adjuncts to the treatment of motor disorders that involve pathological disturbances of the gastrointestinal tachyKinin system. Expand
Peptidergic sensory neurons in the control of vascular functions: mechanisms and significance in the cutaneous and splanchnic vascular beds.
  • P. Holzer
  • Medicine
  • Reviews of physiology, biochemistry and…
  • 1992
Neuropeptides and the microbiota-gut-brain axis.
  • P. Holzer, A. Farzi
  • Biology, Medicine
  • Advances in experimental medicine and biology
  • 2014
TLDR
Although the impact of neuropeptides on the interaction between the gut microbiota and brain awaits to be analysed, biologically active peptides are likely to emerge as neural and endocrine messengers in orchestrating the microbiota-gut-brain axis in health and disease. Expand
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