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NLRP3 gene

Known as: AII, PYPAF1, NLR family, pyrin domain containing 3 
This gene plays a role in both inflammation and apoptosis.
National Institutes of Health

Related topics

Related topics

5 relations
ApoptosisNLRP3 protein, humanNLRP3 wt AllelePositive Regulation of Apoptosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
IL-1 beta breaks tolerance through expansion of CD25+ effector T cells.
IL-1 is a key proinflammatory driver of several autoimmune diseases including juvenile inflammatory arthritis, diseases with… 
Review
2003
Review
2003
ACE inhibitors and AII receptor antagonists in the treatment and prevention of bone marrow transplant nephropathy.
Highly Cited
1992
Highly Cited
1992
Mechanism of angiotensin II-induced proliferation in bovine adrenocortical cells.
The peptide hormone angiotensin-II (AII) is a potent vasoconstrictor and major regulator of aldosterone synthesis. In addition… 
Highly Cited
1991
Highly Cited
1991
Cholesterol efflux from cells to immunopurified subfractions of human high density lipoprotein: LP-AI and LP-AI/AII.
Using immunoaffinity chromatography, we separated human high density lipoprotein (HDL) into two subfractions: LP-AI, in which all… 
Highly Cited
1991
Highly Cited
1991
DuP 532: a second generation of nonpeptide angiotensin II receptor antagonists.
Highly Cited
1990
Highly Cited
1990
Angiotensin II surface receptor coupling to inositol trisphosphate formation in vascular smooth muscle cells.
Highly Cited
1985
Highly Cited
1985
Identification of apolipoproteins involved in the interaction of human high density lipoprotein3 with receptors on cultured cells.
Human high density lipoprotein (HDL), devoid of apolipoproteins E or B, binds with high affinity and specificity to cultured… 
Highly Cited
1985
Highly Cited
1985
AUGMENTATION OF THE RESPONSE TO CRF IN MAN: RELATIVE CONTRIBUTIONS OF ENDOGENOUS ANGIOTENSIN AND VASOPRESSIN
The plasma ACTH response to corticotrophin releasing factor (CRF) was studied in seven normal individuals. Five subjects were… 
Highly Cited
1984
Highly Cited
1984
Local generation of angiotensin II as a mechanism of regulation of peripheral vascular tone in the rat.
Renin is present in vascular smooth muscle cells and has been shown to coexist with angiotensins I (AI) and II (AII) in many cell… 
Highly Cited
1983
Highly Cited
1983
Analysis of angiotensin‐stimulated sodium transport in cultured smooth muscle cells from rat aorta
Angiotensin peptides (AI, AII, AIII) increased the rate of Na+ accumulation by smooth muscle cells (SMC) cultured from rat aorta… 
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