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NLRP3 protein, human

Known as: Angiotensin/Vasopressin Receptor AII/AVP-Like, Cryopyrin, PYRIN-containing Apaf1-like protein 1, human 
NACHT, LRR and PYD domains-containing protein 3 (1034 aa, ~118 kDa) is encoded by the human NLRP3 gene. This protein plays a role in the modulation… 
National Institutes of Health

Related topics

Related topics

10 relations
ApoptosisApoptosis PromoterGenes, RegulatorHomo sapiens

Broader (1)

NLR Family, Pyrin Domain-Containing 3 Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Wirksamkeits- und Sicherheitsanalyse von Off-label-Biologikatherapien bei Patienten mit autoinflammatorischen Erkrankungen
ZusammenfassungZielRetrospektive Erfassung und Evaluation der Wirksamkeit und Sicherheit von Off-label Biologikatherapien bei… 
2018
2018
The First Report on Clinical Manifestation of Cryopyrin-Associated Periodic Syndrome in Korean Children
Purpose: The aim of this study was to evaluate the clinical characteristics of children diagnosed as cryopyrin-associated… 
2017
2017
Novel evidences of atypical manifestations in cryopyrin-associated periodic syndromes.
OBJECTIVES Cryopyrin-associated periodic syndromes (CAPS) usually start during infancy as an urticarial-like rash and a marked… 
2016
2016
FRI0503 Efficacy and Safety of Canakinumab in Patients with Cryopyrin Associated Periodic Syndromes: An Open-Label, Phase-III, Extension Study
Background Cryopyrin-Associated Periodic Syndrome (CAPS), a rare hereditary auto inflammatory disorder, constitutes 3 phenotypes… 
2014
2014
Successful Management of Cryopyrin-Associated Periodic Syndrome With Canakinumab in Infancy
Neonatal onset multisystem inflammatory disease (NOMID)/chronic infantile neurologic cutaneous and articular (CINCA) syndrome is… 
2014
2014
Cryopyrin-associated periodic fever syndrome presenting with fevers and serositis related to a novel NLRP3 gene mutation.
2013
2013
Как распознать пациента с аутовоспалительным синдромом: клинико-диагностические алгоритмы
Autoinflammatory syndromes (AISs) are a group of predominantly hereditary diseases associated with the spontaneous uncontrolled… 
2012
2012
“Mutation negative” familial cold autoinflammatory syndrome (FCAS) in an 8-year-old boy: clinical course and functional studies
Cryopyrinopathies are a subgroup of autoinflammatory syndromes. Most cases have mutations in the CIAS1/NLRL3 gene, encoding the… 
Review
2010
Review
2010
Canakinumab for treatment of cryopyrin-associated periodic syndrome
Importance of the field: Autoinflammatory syndromes such as cryopyrin-associated periodic syndromes (CAPS) place a heavy burden… 
2007
2007
Cryopyrin-associated autoinflammatory syndrome: a new mutation
Patients with mutations in the gene for cold-induced autoinflammatory syndrome (CIAS1; cryopyrin) have a wide range of disease… 
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