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The acute effects of oral ethanol on the hypothalamic‐pituitary‐adrenal axis in normal human subjects
OBJECTIVE To evaluate the acute effects of oral ethanol on the hypothalamic‐pituitary‐adrenal axis in normal human subjects and, in particular, to examine the effect of background alcohol intake and… Expand
Arginine Vasopressin Is Associated with Hypercortisolemia and Suicide Attempts in Depression
- Wattrick J Inder, R. Donald, T. Prickett, C. Frampton, P. Joyce
- Biological Psychiatry
- 15 October 1997
Activation of the hypothalamic–pituitary–adrenal (HPA) axis is commonly seen in patients suffering from depression (Charlton and Ferrier 1989). Raised plasma concentrations of cortisol may be present… Expand
Generation of action potentials in a mathematical model of corticotrophs.
- A. LeBeau, A. B. Robson, A. McKinnon, R. Donald, J. Sneyd
- Chemistry, Medicine
- Biophysical journal
- 1 September 1997
Corticotropin-releasing hormone (CRH) is an important regulator of adrenocorticotropin (ACTH) secretion from pituitary corticotroph cells. The intracellular signaling system that underlies this… Expand
PITUITARY‐OVARIAN FUNCTION IN NORMAL WOMEN DURING THE MENOPAUSAL TRANSITION
The excretion of follicle stimulating hormone (FSH), luteinizing hormone (LH), oestrogens and pregnanediol was measured in weekly urine samples collected for 14–87 weeks (median, 43 weeks) from… Expand
Glycerol prevents loss of immunoreactive follicle-stimulating hormone and luteinizing hormone from frozen urine.
- J. Livesey, H. K. Roud, M. Metcalf, R. Donald
- Biology, Medicine
- The Journal of endocrinology
- 1 September 1983
First morning urine samples were collected from both menstruant and post-menopausal women and stored at -25 degrees C. Immunoreactive FSH disappeared from these samples (t1/2 = 30 days), ultimately… Expand
Low‐dose growth hormone replacement lowers plasma leptin and fat stores without affecting body mass index in adults with growth hormone deficiency
- C. Florkowski, G. Collier, P. Zimmet, J. Livesey, E. Espiner, R. Donald
- Biology, Medicine
- Clinical endocrinology
- 1 December 1996
OBJECTIVE The ob gene product, leptin, is considered to be a marker of adipose tissue mass and a possible homeostatic regulator of body mass. Our objective was to examine the effect of GH replacement… Expand
Dynamics of the Regulation of the Hypothalamo–Pituitary–Adrenal (HPA) Axis Determined Using a Nonsurgical Method for Collecting Pituitary Venous Blood from Horses
Since 1985, we have applied our nonsurgical technique for collecting pituitary venous (PitVen) blood from ambulatory horses to investigate the regulation of adrenocorticotropic hormone (ACTH)… Expand
Plasma corticotrophin releasing factor and vasopressin responses to exercise in normal man
Summary. objective To evaluate the hypothalamo‐pitultary‐adrenal (HPA) response to both mild and Intense exercise.
Reduction in basal afternoon plasma ACTH during early treatment of depression with fluoxetine
Abstract. Rationale: Subjects with depression may exhibit activation of the hypothalamic-pituitary-adrenal (HPA) axis, but little is known about the response of basal hormone levels to antidepressant… Expand
Prolonged exercise increases peripheral plasma ACTH, CRH, and AVP in male athletes.
- W. Inder, J. Hellemans, M. Swanney, T. Prickett, R. Donald
- Journal of applied physiology
- 1 September 1998
We wished to determine whether the increased ACTH during prolonged exercise was associated with changes in peripheral corticotropin-releasing hormone (CRH) and/or arginine vasopressin (AVP). Six male… Expand