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N-propionylmannosamine

National Institutes of Health

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Hexosamines

Papers overview

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2015
2015
N-Propionylmannosamine stimulates axonal elongation in a murine model of sciatic nerve injury
Increasing evidence indicates that sialic acid plays an important role during nerve regeneration. Sialic acids can be modified in… 
2015
2015
N-Propionylmannosamine: using biochemical glycoengineering to promote peripheral nerve regeneration
The peripheral nervous system, in contrast to the central nervous system, is capable of spontaneous regeneration. However, nerve… 
2015
2015
In vivo stimulation of early peripheral axon regeneration by N-propionylmannosamine in the presence of polysialyltransferase ST8SIA2
AbstractThe key enzyme of sialic acid (Sia) biosynthesis is the bifunctional UDP-N-acetylglucosamine 2-epimerase/ManNAc kinase… 
2010
2010
N-Propionylmannosamine-induced over-expression and secretion of thioredoxin leads to neurite outgrowth of PC12 cells.
2010
2010
Invasion of Trypanosoma cruzi into host cells is impaired by N-propionylmannosamine and other N-acylmannosamines
The etiologic agent of Chagas’ disease, Trypanosoma cruzi, is widely distributed in South America, affecting millions of people… 
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