N-Propionylmannosamine: using biochemical glycoengineering to promote peripheral nerve regeneration

@article{Koulaxouzidis2015NPropionylmannosamineUB,
  title={N-Propionylmannosamine: using biochemical glycoengineering to promote peripheral nerve regeneration},
  author={Georgios Koulaxouzidis and Werner Reutter and Christian Witzel},
  journal={Neural Regeneration Research},
  year={2015},
  volume={10},
  pages={1947 - 1948}
}
The peripheral nervous system, in contrast to the central nervous system, is capable of spontaneous regeneration. However, nerve reconstruction in the peripheral nervous system remains a major challenge, as the functional outcomes following nerve repair are variable. Quantitative parameters such as the number of regenerating axons and degree of myelination are crucial, but correct axon target organ allocation, time to regeneration and target organ quality are also equally important. After…