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Electrical Stimulation Promotes Motoneuron Regeneration without Increasing Its Speed or Conditioning the Neuron
TLDR
Electrical stimulation promotes the onset of motor axon regeneration without increasing its speed, and suggests a combined approach to improving the outcome of nerve repair, beginning with stimulation to recruit all motoneurons across the repair, followed by other treatments to speed and prolong axonal elongation.
Pathway sampling by regenerating peripheral axons
TLDR
The apparent wandering of axons across the repair defies surgical control and mandates a biological approach to reuniting severed axons with appropriate distal pathways, explaining the failure of refined surgical techniques to restore normal function after nerve injury.
Electrical Nerve Stimulation Enhances Perilesional Branching after Nerve Grafting but Fails to Increase Regeneration Speed in a Murine Model.
TLDR
The morphological data analysis revealed that electrical stimulation in this model increases axonal crossing of the repair site and promotes homogeneous perilesional branching, but does not affect regeneration speed.
Fibrin glue repair leads to enhanced axonal elongation during early peripheral nerve regeneration in an in vivo mouse model
TLDR
Fibrin glue nerve coaptation seems to be a promising alternative to microsuture repair and significantly reduced surgical repair time, and the increase in arborizing axons could be another explanation for better functional and electrophysiological results after fibr in glue repair.
Detecting of breast cancer metastasis by means of regional lymph node sampling during autologous breast reconstruction – a screening of 519 consecutive patients
TLDR
Routine sampling of internal mammary lymph nodes at the time of microvascular breast reconstruction is easy to perform and is a useful tool to identify women, who might require additional treatment and increase cancer-free survival.
Impact of radiation therapy on healing and stability of vascularized bone grafts in a dog model
TLDR
A large animal model is established for further determination of different strategies of radiotherapy in combination with vascularized bone transfers, and a significant worsening in bone healing and stability after pre‐ and postoperative radiation therapy to the wound bed and bone grafts is demonstrated.
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