Mitogen-Activated Protein Kinase 12

Systemic signalling is indispensable for the coordination of diverse physiological processes during development, defence and… Expand

Our understanding of the X-linked lymphoproliferative syndrome (XLP) has advanced significantly in the last two years. The gene… Expand

ABSTRACT The p38 group of kinases belongs to the mitogen-activated protein (MAP) kinase superfamily with structural and… Expand

The differentiation of C2C12 myoblasts to myotubes was found to be accompanied by a strong activation of p70 S6 kinase and the… Expand

BACKGROUND Specific inhibitors of protein kinases have great therapeutic potential, but the molecular basis underlying their… Expand

Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase compete with ATP for binding. Mutation of 23 residues in… Expand

A novel homologue of p38 MAP kinase, called SAPK4, has been cloned which shares 61% amino acid identity with p38 and is expressed… Expand

Stress‐activated protein kinase‐3 (SAPK3), a recently described MAP kinase family member with a widespread tissue distribution… Expand

A cDNA was cloned that encodes human stress‐activated protein kinase‐4 (SAPK4), a novel MAP kinase family member whose amino acid… Expand

The paired helical filament, which comprises the major fibrous element of the neurofibrillary lesions of Alzheimer's disease, is… Expand