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MAPK12 wt Allele

Known as: PRKM12, ERK3, SAPK3 
Human MAPK12 wild-type allele is located in the vicinity of 22q13.33 and is approximately 9 kb in length. This allele, which encodes mitogen… 
National Institutes of Health

Related topics

Related topics

18 relations
22q13.33Cell Cycle ControlHomo sapiensMAPK Signaling Pathway

Broader (1)

MAPK12 gene

Papers overview

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Highly Cited
2009
Highly Cited
2009
ROS, Hsp27, and IKK&bgr; mediate dextran sodium sulfate (DSS) activation of I&kgr;Ba, NF&kgr;B, and IL‐8
Background: Dextran sodium sulfate (DSS) is a sulfated polysaccharide that has been very widely used to induce inflammation in… 
Highly Cited
2006
Highly Cited
2006
p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion.
Ras is believed to stimulate invasion and growth by different effector pathways, and yet, the existence of such effectors under… 
2004
2004
p38gamma MAPK regulation of glucose transporter expression and glucose uptake in L6 myotubes and mouse skeletal muscle.
Skeletal muscle expresses at least three p38 MAPKs (alpha, beta, gamma). However, no studies have examined the potential… 
2003
2003
Phorbol Ester-dependent Activation of Peroxiredoxin I Gene Expression via a Protein Kinase C, Ras, p38 Mitogen-activated Protein Kinase Signaling Pathway*
The antioxidant protein peroxiredoxin (Prx) I is a thioredoxin peroxidase that is involved in the regulation of proliferation and… 
2003
2003
Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN.
PKNalpha is a fatty acid- and Rho-activated serine/threonine protein kinase having a catalytic domain homologous to members of… 
Highly Cited
2002
Highly Cited
2002
Cardiac expression and subcellular localization of the p38 mitogen-activated protein kinase member, stress-activated protein kinase-3 (SAPK3).
Despite the interest in the roles that mitogen-activated protein kinases (MAPKs) play in the heart, the role of the different… 
2002
2002
Potent transforming activity of the small GTP‐binding protein Rit in NIH 3T3 cells: evidence for a role of a p38γ‐dependent signaling pathway
2000
2000
Cisplatin and UV radiation induce activation of the stress-activated protein kinase p38gamma in human melanoma cells.
The p38 alpha mitogen-activated protein kinase has been implicated in the cellular response to genotoxic agents. Here we show… 
Highly Cited
1999
Highly Cited
1999
Human JIK, a Novel Member of the STE20 Kinase Family That Inhibits JNK and Is Negatively Regulated by Epidermal Growth Factor*
Mammalian members related to Saccharomyces cerevisiae serine/threonine kinase STE20 can be divided into two subfamilies based on… 
Highly Cited
1997
Highly Cited
1997
Cloning and Characterization of a Human STE20-like Protein Kinase with Unusual Cofactor Requirements*
We cloned and characterized a novel human member of the STE20 serine/threonine protein kinase family named mst-3. Based on its… 
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