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MAPK Signaling Pathway

The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell… 
National Institutes of Health

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Papers overview

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2016
2016
Baicalein and U 0126 suppress human breast cancer cell line MCF-7 through regulating MAPK signaling pathway
Backgroud: Baicalein is a member of active falvonoids compounds with anti-bacterial, anti-inflammatory, and anti-infection effect… 
2016
2016
Crocin protects retinal pigment epithelial cells from oxidative stress through suppression of the MAPK signaling pathway
Oxidative stress damage to retinal pigment epithelial (RPE) cells is thought to play a critical role in the pathogenesis of age… 
2015
2015
The Synergistic Mechanism of Pemetrexed Followed by Kanglaite was due to KLT Subsequently Inhibiting the Pemetrexed-Activated MAPK Signaling Pathway.
BACKGROUND Kanglaite (KLT) can enhance the cytotoxic effects of chemotherapy; however, the underlying mechanism remains unclear… 
2014
2014
Abstract 5297: Role of p38 MAPK signaling pathway in the inhibition of breast tumor progression induced by Glypican-3 (GPC3)
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Glypican-3 (GPC3) is expressed in normal mammary tissues… 
2014
2014
HMGB1 enhances embryonic neural stem cell proliferation by activating the MAPK signaling pathway
Neural stem cells (NSCs) are involved in neural tube formation. As the high-mobility group box 1 (HMGB1) protein is involved in… 
Review
2013
Review
2013
[Advances in research on the MAPK signal transduction pathway of Echinococcus].
Mitogen-activated protein kinase (MAPK) is an important signaling transduction molecules, which can enter the nucleus and… 
2012
2012
Tamoxifen enhances chemotherapeutic efficacy of C6‐ ceramide and increases induction of apoptosis in human colorectal cancer cells by upregulation of MAPK signaling pathway and down‐regulation of…
Resistance to chemotherapy is a critical barrier to successful treatment of colorectal cancer (CRC). Ceramide, because of its… 
2009
2009
N-acetylcysteine blocked hypoxia-reoxygenation induced apoptosis through ROS-p38 MAPK signaling pathway in neonatal rat cardiomyocytes
Objective Previous investigations have shown that N-acetylcysteine (NAC) could regulate diverse cell type's apoptosis. The… 
2002
2002
The role of mechanical stress in skeletal myocytes : MAPK signal transduction pathways
1 Department of Biochemistry and Cell Biology Rice University Houston, TX 77005 dbarr@rice.edu The idea of signal transduction… 
1999
1999
p38 MAPK signal transduction pathway
Mitogen-activated protein kinase (MAPK) involved in many cellular process,such as,cell growth, development,division, programmed…