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AKT1 wt Allele

Known as: RAC-PK-Alpha, v-akt Murine Thymoma Viral Oncogene Homolog 1 wt Allele, PKB 
Human AKT1 wild-type allele is located in the vicinity of 14q32.32 and is approximately 26 kb in length. This allele, which encodes RAC-alpha serine… 
National Institutes of Health

Related topics

Related topics

44 relations
14q32.3AKT Signaling PathwayAdipocytokine Signaling PathwayAngiogenesis Pathway

Broader (1)

AKT1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Akt is frequently activated in HER2/neu‐positive breast cancers and associated with poor prognosis among hormone‐treated patients
Akt/PKB is a serine/threonine kinase that plays an important role in survival when cells are exposed to different apoptotic… 
Highly Cited
2004
Highly Cited
2004
The effect of dietary ractopamine concentration and duration of feeding on growth performance, carcass characteristics, and meat quality of finishing pigs.
A total of 400 barrows from Dekalb EB and 83 terminal sires mated to 43 and 45 maternal lines were used to evaluate the effects… 
Highly Cited
2003
Highly Cited
2003
Calcium Signaling Regulates Translocation and Activation of Rac*
Rac is activated in response to various stimuli including growth factors and by adhesion to the extracellular matrix. However… 
Highly Cited
2003
Highly Cited
2003
Engulfment of Apoptotic Cells Is Negatively Regulated by Rho-mediated Signaling*
The rapid and efficient phagocytosis of apoptotic cells plays a critical role in preventing secondary necrosis, inflammation as… 
Review
2003
Review
2003
Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch.
The small G protein Rac has been implicated in multiple cardiovascular processes. Rac has two major functions: 1) it regulates… 
Highly Cited
2002
Highly Cited
2002
Toward a PKB inhibitor: modification of a selective PKA inhibitor by rational design.
Protein kinase B/Akt (PKB) is an anti-apoptotic protein kinase that has strongly elevated activity in human malignancies. We… 
Highly Cited
2001
Highly Cited
2001
Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer
RAC 3, one of the p160 family of co-activators is known to enhance the transcriptional activity of a number of steroid receptors… 
Highly Cited
2000
Highly Cited
2000
Activation of RhoA by Thrombin in Endothelial Hyperpermeability: Role of Rho Kinase and Protein Tyrosine Kinases
Endothelial cells (ECs) actively regulate the extravasation of blood constituents. On stimulation by vasoactive agents and… 
Highly Cited
1996
Highly Cited
1996
Effect of ractopamine on growth performance, carcass composition, and cutting yields of pigs slaughtered at 107 and 125 kilograms.
At approximately 68 kg live weight, crossbred barrows and gilts (n = 144) were allocated to be fed to one of two weight end… 
Highly Cited
1993
Highly Cited
1993
Interrelationships between sex and ractopamine on protein and lipid deposition in rapidly growing pigs.
Sixty pigs were used to investigate the effects of two levels of dietary ractopamine (RAC; 0 and 20 mg/kg) and three sex types… 
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