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MAPK12 protein, human

Known as: MAP Kinase p38 Gamma, ERK-6, SAPK3 
Mitogen-activated protein kinase 12 (367 aa, ~42 kDa) is encoded by the human MAPK12 gene. This protein is involved in cell cycle arrest, serine… 
National Institutes of Health

Related topics

Related topics

23 relations

Broader (3)

Calcium-Calmodulin-Dependent Protein KinasesCalcium/calmodulin-dependent protein kinaseMitogen-Activated Protein Kinase 12
Cell Cycle ControlEnzyme GeneHeartMAP Kinase Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The implication from RAS/RAF/ERK signaling pathway increased activation in epirubicin treated triple negative breast cancer
Background Triple negative breast cancer (TNBC) is not sensitive to RAS/RAF/ERK signaling pathway (ERK pathway) targeting therapy… 
2017
2017
miR-187 inhibits tumor growth and invasion by directly targeting MAPK12 in osteosarcoma
MicroRNAs (miRNAs/miRs) play crucial roles in cancer development and progression. The purposes of this study were to investigate… 
Highly Cited
2016
Highly Cited
2016
Cellular localization of NRF2 determines the self-renewal and osteogenic differentiation potential of human MSCs via the P53–SIRT1 axis
The Wnt inhibitor Dickkopf-1 (DKK-1) has been associated with the occurrence of bone metastases in osteotropic prostate cancer by… 
2015
2015
Ex Vivo Perfusion With Adenosine A2A Receptor Agonist Enhances Rehabilitation of Murine Donor Lungs After Circulatory Death
Background Ex vivo lung perfusion (EVLP) enables assessment and rehabilitation of marginal donor lungs before transplantation. We… 
2015
2015
Gene structure, molecular characterization and transcriptional expression of two p38 isoforms (MAPK11 and MAPK14) from rock bream (Oplegnathus fasciatus).
Highly Cited
2014
Highly Cited
2014
Pro-oncogenic role of alternative p38 mitogen-activated protein kinases p38γ and p38δ, linking inflammation and cancer in colitis-associated colon cancer.
p38 MAPK signaling has been implicated in the regulation of processes leading to cancer development and progression. Chronic… 
Highly Cited
2009
Highly Cited
2009
ROS, Hsp27, and IKK&bgr; mediate dextran sodium sulfate (DSS) activation of I&kgr;Ba, NF&kgr;B, and IL‐8
Background: Dextran sodium sulfate (DSS) is a sulfated polysaccharide that has been very widely used to induce inflammation in… 
Highly Cited
2004
Highly Cited
2004
Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2.
SAPK3 (stress-activated protein kinase-3, also known as p38gamma) is a member of the mitogen-activated protein kinase family; it… 
Highly Cited
2004
Highly Cited
2004
Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas
It is becoming increasingly clear that alternative splicing enables the complex development and homeostasis of higher organisms… 
2004
2004
Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3.
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