Calcium-Calmodulin-Dependent Protein Kinases

Known as: Calmodulin-Kinase, Calcium-Calmodulin-Dependent Protein Kinases [Chemical/Ingredient], Calmodulin Dependent Protein Kinases 
A CALMODULIN-dependent enzyme that catalyzes the phosphorylation of proteins. This enzyme is also sometimes dependent on CALCIUM. A wide range of… (More)
National Institutes of Health

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Narrower (9)

CCK1 protein, Chlamydomonas moewusiiCDKL2 protein, humanCaki protein, DrosophilaMAPK12 protein, human
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Calcium/calmodulin-dependent protein kinaseCell Cycle ProteinsExtracellular Signal Regulated KinasesIn Blood
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Broader (1)

Protein-Serine-Threonine Kinases

Papers overview

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2013
2013
Focal adhesion kinases and calcium/calmodulin-dependent protein kinases regulate protein tyrosine phosphorylation in stallion sperm.
Protein tyrosine phosphorylation (PY) is a hallmark of sperm capacitation. In stallion sperm, calcium inhibits PY at pH <7.8… (More)
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Highly Cited
2005
Highly Cited
2005
Calmodulin-dependent kinase kinase/calmodulin kinase I activity gates extracellular-regulated kinase-dependent long-term potentiation.
Intracellular Ca2+ and protein phosphorylation play pivotal roles in long-term potentiation (LTP), a cellular model of learning… (More)
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Highly Cited
2004
Highly Cited
2004
Redox regulation of the calcium/calmodulin-dependent protein kinases.
Reactive oxygen intermediates (ROI) have been viewed traditionally as damaging to the cell. However, a predominance of evidence… (More)
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Highly Cited
2003
Highly Cited
2003
The Arabidopsis CDPK-SnRK superfamily of protein kinases.
The CDPK-SnRK superfamily consists of seven types of serine-threonine protein kinases: calcium-dependent protein kinase (CDPKs… (More)
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Highly Cited
2001
Highly Cited
2001
Activity-dependent CREB phosphorylation: convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway.
The cAMP-responsive element binding protein (CREB), a key regulator of gene expression, is activated by phosphorylation on Ser… (More)
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Highly Cited
1998
Highly Cited
1998
Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning.
The calcium-calmodulin-dependent kinase II (CaMKII) is required for hippocampal long-term potentiation (LTP) and spatial learning… (More)
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Highly Cited
1994
Highly Cited
1994
Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity.
The cAMP response element-binding protein (CREB) has been shown to mediate transcriptional activation of genes in response to… (More)
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Highly Cited
1992
Highly Cited
1992
Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice.
As a first step in a program to use genetically altered mice in the study of memory mechanisms, mutant mice were produced that do… (More)
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Highly Cited
1992
Highly Cited
1992
Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice.
Although long-term potentiation (LTP) has been studied as the mechanism for hippocampus-dependent learning and memory, evidence… (More)
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Highly Cited
1991
Highly Cited
1991
Inositol trisphosphate receptor: phosphorylation by protein kinase C and calcium calmodulin-dependent protein kinases in reconstituted lipid vesicles.
We have previously demonstrated that the inositol 1,4,5-trisphosphate (IP3) receptor is phosphorylated by cyclic AMP-dependent… (More)
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