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Calcium-Calmodulin-Dependent Protein Kinases
Known as:
Calmodulin-Kinase
, Calcium-Calmodulin-Dependent Protein Kinases [Chemical/Ingredient]
, Calmodulin Dependent Protein Kinases
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A CALMODULIN-dependent enzyme that catalyzes the phosphorylation of proteins. This enzyme is also sometimes dependent on CALCIUM. A wide range of…
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National Institutes of Health
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Related topics
Related topics
22 relations
Narrower (9)
CCK1 protein, Chlamydomonas moewusii
CDKL2 protein, human
Caki protein, Drosophila
MAPK12 protein, human
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Calcium/calmodulin-dependent protein kinase
Cell Cycle Proteins
Extracellular Signal Regulated Kinases
In Blood
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Broader (1)
Protein-Serine-Threonine Kinases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Reactive Oxygen Species–Activated Ca/Calmodulin Kinase II&dgr; Is Required for Late INa Augmentation Leading to Cellular Na and Ca Overload
S. Wagner
,
Hanna M. Ruff
,
+9 authors
L. Maier
Circulation Research
2011
Corpus ID: 2374790
Rationale: In heart failure Ca/calmodulin kinase (CaMK)II expression and reactive oxygen species (ROS) are increased. Both ROS…
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Highly Cited
2006
Highly Cited
2006
Death, Cardiac Dysfunction, and Arrhythmias Are Increased by Calmodulin Kinase II in Calcineurin Cardiomyopathy
M. Khoo
,
Jingdong Li
,
+17 authors
M. Anderson
Circulation
2006
Corpus ID: 33582890
Background— Activation of cellular Ca2+ signaling molecules appears to be a fundamental step in the progression of cardiomyopathy…
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Highly Cited
2004
Highly Cited
2004
Redox Regulation of the Calcium/Calmodulin-dependent Protein Kinases*
C. Howe
,
Michelle M Lahair
,
J. McCubrey
,
R. Franklin
Journal of Biological Chemistry
2004
Corpus ID: 25236798
Reactive oxygen intermediates (ROI) have been viewed traditionally as damaging to the cell. However, a predominance of evidence…
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Highly Cited
2003
Highly Cited
2003
From Calcium to NF-κB Signaling Pathways in Neurons
A. Lilienbaum
,
A. Israël
Molecular and Cellular Biology
2003
Corpus ID: 27913863
ABSTRACT NF-κB plays crucial roles in the nervous system, including potential roles in long-term responses to synaptic plasticity…
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Highly Cited
2002
Highly Cited
2002
Activation and induction of NUR77/NURR1 in corticotrophs by CRH/cAMP: involvement of calcium, protein kinase A, and MAPK pathways.
D. Kovalovsky
,
D. Refojo
,
+6 authors
E. Arzt
Molecular Endocrinology
2002
Corpus ID: 8185440
Nur factors are critical for proopiomelanocortin (POMC) induction by CRH in corticotrophs, but the pathways linking CRH to Nur…
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Highly Cited
1994
Highly Cited
1994
Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release.
R. A. Steinhardt
,
Guo-Qiang Bi
,
J. Alderton
Science
1994
Corpus ID: 20808878
After injury to the cell membrane, rapid resealing of the membrane occurs with little loss of intracellular contents. This…
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Highly Cited
1994
Highly Cited
1994
Roles of calmodulin-dependent protein kinases and phosphatase in calcium-dependent transcription of immediate early genes.
H. Enslen
,
T. Soderling
Journal of Biological Chemistry
1994
Corpus ID: 31927175
Recent studies indicate multiple mechanisms are involved in Ca2+ stimulation of gene expression. We have used cell-permeable…
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Highly Cited
1992
Highly Cited
1992
Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice.
Alcino J. Silva
,
Charles F. Stevens
,
S. Tonegawa
,
Yanyan Wang
Science
1992
Corpus ID: 43611837
As a first step in a program to use genetically altered mice in the study of memory mechanisms, mutant mice were produced that do…
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Highly Cited
1985
Highly Cited
1985
Dephosphorylation of Microtubule‐Associated Protein 2, τ Factor, and Tubulin by Calcineurin
S. Goto
,
Hideyuki Yamamoto
,
K. Fukunaga
,
T. Iwasa
,
Y. Matsukado
,
E. Miyamoto
Journal of Neurochemistry
1985
Corpus ID: 22370774
Abstract: Calcineurin dephosphorylated microtubule‐associated protein 2 (MAP2) and τ factor phosphorylated by cyclic AMP…
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Highly Cited
1981
Highly Cited
1981
Two calcium/calmodulin-dependent protein kinases, which are highly concentrated in brain, phosphorylate protein I at distinct sites.
M. Kennedy
,
P. Greengard
Proceedings of the National Academy of Sciences…
1981
Corpus ID: 25888618
Two calcium-stimulated protein kinase activities (ATP:protein phosphotransferase, EC 2.7.1.37) that phosphorylate protein I, a…
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