D. Gérard

Publications52
h-index20
Citations1,525
Highly Influential Citations34
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Conformational behaviour of the active and inactive forms of the nucleocapsid NCp7 of HIV-1 studied by 1H NMR.
The nucleocapsid protein NCp7 of the human immunodeficiency virus type I (HIV-1) is a 72 amino acid peptide containing two zinc fingers of the type CX2CX4HX4C linked by a short basic sequence… Expand
  • 128
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Properties and growth mechanism of the ordered aggregation of a model RNA by the HIV-1 nucleocapsid protein: an electron microscopy investigation.
NCp7, the nucleocapsid protein of the human immunodeficiency virus type 1, induces an ordered aggregation of RNAs, a mechanism that is thought to be involved in the NCp7-induced promotion of nucleic… Expand
  • 78
  • 6
Nucleic acid sequence discrimination by the HIV-1 nucleocapsid protein NCp7: a fluorescence study.
The critical functions of the HIV-1 nucleocapsid protein NCp7 in genomic RNA packaging and reverse transcription, essentially rely on interactions with nucleic acids. A significant progress in the… Expand
  • 124
  • 4
Ordered aggregation of ribonucleic acids by the human immunodeficiency virus type 1 nucleocapsid protein.
The nucleocapsid protein NCp7, which is the major genomic RNA binding protein of human immunodeficiency virus type 1, plays an important role in several key steps of the viral life cycle. Many of the… Expand
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Determinants of coenzyme specificity in glyceraldehyde-3-phosphate dehydrogenase: role of the acidic residue in the fingerprint region of the nucleotide binding fold.
On the basis of the three-dimensional structure of the glycolytic NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and of sequence comparison with the photosynthetic NAD(P)-dependent… Expand
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Heparin-induced conformational change and activation of mucus proteinase inhibitor.
Low molecular mass heparin (5.1 kDa) forms a tight complex with mucus proteinase inhibitor, the physiologic neutrophil elastase inhibitor of the upper respiratory tract. This binding strongly… Expand
  • 63
  • 2
Fluorescence study of tobacco mosaic virus protein
Abstract Protein fluorescence properties of tobacco mosaic virus [3 Trp residues per monomer (positions 17, 52, 152)] and of two tobacco mosaic virus mutants [green tomato atypical mosaic virus, 2… Expand
  • 16
  • 2
Fluorescent study of tobacco mosaic virus protein.
Protein fluorescence properties of tobacco mosaic virus [3 Trp residues per monomer (positions 17, 52, 152)] and of two tobacco mosaic virus mutants [green tomato atypical mosaic virus, 2 Trp (52,… Expand
  • 5
  • 2
Binding of the HIV-1 Nucleocapsid Protein to the Primer tRNA, inVitro, Is Essentially Not Specific (*)
The nucleocapsid protein NCp7 of human immunodeficiency virus, type 1, is a key component in the viral life cycle. Since, the first common step of all reported NCp7 activities corresponds to a… Expand
  • 73
  • 1
A comparison of the fluorescence properties of TMA-DPH as a probe for plasma membrane and for endocytic membrane.
In earlier studies, the fluorescence probe 1-(4-(trimethylamino)phenyl)-6-phenylhexa-1,3,5-triene (TMA-DPH) was shown to interact with living cells by instantaneous incorporation into the plasma… Expand
  • 63
  • 1