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Microtubules

Known as: cytoplasmic microtubule, Micro Tubule, Micro-tubule 
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The… 
National Institutes of Health

Related topics

Related topics

43 relations
ASPM protein, humanCytoskeletonDNM2 protein, humanEndoplasm

Broader (5)

AxonemeMicrotubule BundleMicrotubule cytoskeletonaxonemal outer doublet

Narrower (7)

Peripheral doublet microtubule of axoneme of ciliumPlus end of microtubuledendritic microtubulemicrotubule end

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Microtubules and resistance to tubulin-binding agents
Nature Reviews Cancer 10, 194–204 (2010) On page 202 of this article, extracellular matrix transforming growth factor-β1 (TGFβ1… 
Highly Cited
2005
Highly Cited
2005
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
During cell division, mitotic spindles are assembled by microtubule-based motor proteins. The bipolar organization of spindles is… 
Review
2003
Review
2003
Mechanisms of Taxol resistance related to microtubules
Since its approval by the FDA in 1992 for the treatment of ovarian cancer, the use of Taxol has dramatically increased. Although… 
Highly Cited
2001
Highly Cited
2001
mDia mediates Rho-regulated formation and orientation of stable microtubules
Rho-GTPase stabilizes microtubules that are oriented towards the leading edge in serum-starved 3T3 fibroblasts through an unknown… 
Highly Cited
1997
Highly Cited
1997
Measurement of the force-velocity relation for growing microtubules.
Forces generated by protein polymerization are important for various forms of cellular motility. Assembling microtubules, for… 
Highly Cited
1997
Highly Cited
1997
Bcl2 is the guardian of microtubule integrity.
We have investigated the ability of several drugs commonly used in the treatment of human cancer to induce bcl2 phosphorylation… 
Highly Cited
1989
Highly Cited
1989
Movement of microtubules by single kinesin molecules
Kinesin is a motor protein that uses energy derived from ATP hydrolysis to move organelles along microtubules. Using a new… 
Highly Cited
1987
Highly Cited
1987
Microtubules containing acetylated alpha-tubulin in mammalian cells in culture
The subcellular distribution of microtubules containing acetylated alpha-tubulin in mammalian cells in culture was analyzed with… 
Highly Cited
1986
Highly Cited
1986
Microtubules and the endoplasmic reticulum are highly interdependent structures
The interrelationships of the endoplasmic reticulum (ER), microtubules, and intermediate filaments were studied in the peripheral… 
Highly Cited
1973
Highly Cited
1973
Microtubule assembly in the absence of added nucleotides.
Microtubule assembly is enhanced by the addition of 1 M sucrose or 4 M glycerol to the reassembly mixture. Tubulin can be… 
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