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DNM2 protein, human

Known as: Dynamin-2, EC 3.6.5.5, dynamin 2, human 
Dynamin-2 (870 aa, ~98 kDa) is encoded by the human DNM2 gene. This protein plays a role in both microtubule polymerization and GTP hydrolysis.
National Institutes of Health

Related topics

Related topics

19 relations
Cell Cycle ProgressionCytoskeletal ModelingCytoskeletonDNM2 gene
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Broader (2)

Dynamin 2Dynamin GTPase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Control of MT1-MMP transport by atypical PKC during breast-cancer progression
Significance We characterize a mechanism through which the polarity protein atypical PKCι controls invasion and matrix remodeling… Expand
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2013
2013
Dynamin-2 Regulates Fusion Pore Expansion and Quantal Release through a Mechanism that Involves Actin Dynamics in Neuroendocrine Chromaffin Cells
Over the past years, dynamin has been implicated in tuning the amount and nature of transmitter released during exocytosis… Expand
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2013
2013
Dual role of BAR domain-containing proteins in regulating vesicle release catalyzed by the GTPase, dynamin-2.
Dynamin-2 (Dyn2) is ubiquitously expressed and catalyzes membrane fission during clathrin-mediated endocytosis in nonneuronal… Expand
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Highly Cited
2010
Highly Cited
2010
Expanding the clinical, pathological and MRI phenotype of DNM2-related centronuclear myopathy
Mutations in dynamin-2 (DNM2) cause autosomal dominant centronuclear myopathy (CNM). We report a series of 12 patients from eight… Expand
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Highly Cited
2009
Highly Cited
2009
Cargo and Dynamin Regulate Clathrin-Coated Pit Maturation
Total internal reflection fluorescence microscopy (TIR-FM) has become a powerful tool for studying clathrin-mediated endocytosis… Expand
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2008
2008
Oxidised LDL internalisation by the LOX-1 scavenger receptor is dependent on a novel cytoplasmic motif and is regulated by dynamin-2
The LOX-1 scavenger receptor recognises pro-atherogenic oxidised low-density lipoprotein (OxLDL) particles and is implicated in… Expand
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Highly Cited
2007
Highly Cited
2007
Characterization of Reemerging Chikungunya Virus
An unprecedented epidemic of chikungunya virus (CHIKV) infection recently started in countries of the Indian Ocean area, causing… Expand
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2005
2005
Regulatory role of dynamin-2 in VEGFR-2/KDR-mediated endothelial signaling.
Vascular endothelial growth factor receptor-2 (VEGFR-2, also known as KDR) is a receptor tyrosine kinase (RTK) regulating… Expand
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Highly Cited
2004
Highly Cited
2004
Regulated membrane recruitment of dynamin-2 mediated by sorting nexin 9.
The endocytic proteins sorting nexin 9 (SNX9) and dynamin-2 (Dyn2) assemble in the cytosol as a resting complex, together with a… Expand
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Highly Cited
2003
Highly Cited
2003
Sorting Nexin 9 Participates in Clathrin-mediated Endocytosis through Interactions with the Core Components*
Sorting nexin 9 (SNX9) belongs to a family of proteins, the sorting nexins, that are characterized by the presence of a subclass… Expand
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