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Microtubule Polymerization Process

Known as: Microtubule Polymerization, microtubule assembly 
Microtubule polymerization is a cellular process typically, though not solely, involved in cell motility and cell division. Stabilization of… Expand
National Institutes of Health

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Related topics

10 relations
MAP4MAP4 geneMAP4 wt AlleleNegative Regulation of Microtubule Polymerization
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microtubule nucleation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Colchicine Pharmacokinetics and Mechanism of Action.
Colchicine is a tricyclic, lipid-soluble alkaloid derived from the plant of the Lily family Colchicum autumnale, sometimes called… Expand
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Highly Cited
2002
Highly Cited
2002
CRMP-2 binds to tubulin heterodimers to promote microtubule assembly
Regulated increase in the formation of microtubule arrays is thought to be important for axonal growth. Collapsin response… Expand
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Highly Cited
1999
Highly Cited
1999
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
One of the neuropathological hallmarks of Alzheimer's disease is the neurofibrillary tangle, which contains paired helical… Expand
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Highly Cited
1995
Highly Cited
1995
Nucleation of microtubule assembly by a γ-tubulin-containing ring complex
The highly conserved protein γ-tubulin is required for microtubule nucleation in vivo. When viewed in the electron microscope, a… Expand
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Highly Cited
1992
Highly Cited
1992
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.
Microtubule-associated proteins (MAP), such as tau, modulate the extent and rate of microtubule assembly and play an essential… Expand
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Highly Cited
1986
Highly Cited
1986
Tau protein function in living cells
Tau protein from mammalian brain promotes microtubule polymerization in vitro and is induced during nerve cell differentiation… Expand
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Highly Cited
1984
Highly Cited
1984
Phosphorylation affects the ability of tau protein to promote microtubule assembly.
Tau is a family of closely related proteins known for its ability to copolymerize with tubulin, inducing the formation of… Expand
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Highly Cited
1979
Highly Cited
1979
Promotion of microtubule assembly in vitro by taxol
TAXOL (Fig. 1) was isolated from the plant Taxus brevifolia (western yew) by Wani et al., who reported that the molecule has… Expand
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Highly Cited
1975
Highly Cited
1975
A protein factor essential for microtubule assembly.
A heat stable protein essentail for microtubule assembly has been isolated. This protein, which we designate tau (tau), is… Expand
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Highly Cited
1972
Highly Cited
1972
Microtubule Formation in vitro in Solutions Containing Low Calcium Concentrations
Isolated rat brain tubulin can be repolymerized in vitro in solutions containing adenosine triphosphate or guanosine triphosphate… Expand
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