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microtubule nucleation

The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule… 
National Institutes of Health

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Broader (1)

Microtubule Polymerization Process
regulation of microtubule nucleation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Binding of alpha‐fodrin to gamma‐tubulin accounts for its role in the inhibition of microtubule nucleation
Non‐erythroid spectrin or fodrin is present as part of the γ‐tubulin ring complex (γ‐TuRC) in brain tissue and brain derived… 
2018
2018
XMAP215 joins microtubule nucleation team
De novo assembly of microtubules, nucleation, has remained surprisingly enigmatic, considering that microtubules are polymers of… 
2018
2018
Dissecting Protein Complexes in Branching Microtubule Nucleation Using Meiotic Xenopus Egg Extracts.
The mitotic spindle is the microtubule-based apparatus that reliably segregates chromosomes during cell division. Recently, it… 
Review
2006
Review
2006
Microtubule nucleation: gamma-tubulin and beyond.
Centrosomes and their fungal equivalents, spindle pole bodies (SPBs), are the main microtubule (MT)-organizing centers in… 
2004
2004
Characterization of the TPX 2 Domains Involved in Microtubule Nucleation and Spindle Assembly in Xenopus Egg Extracts
TPX2 has multiple functions during mitosis, including microtubule nucleation around the chromosomes and the targeting of Xklp2… 
2002
2002
Regulation of tubulin synthesis and cell cycle progression in mammalian cells by γ‐tubulin‐mediated microtubule nucleation
We have previously shown that γ‐tubulin, the third member of the tubulin family that functions in microtubule nucleation, when… 
2000
2000
Reconstitution of microtubule nucleation potential in centrosomes isolated from Spisula solidissima oocytes.
Treatment of isolated Spisula solidissima centrosomes with KI removes (gamma)-tubulin, 25 nm rings, and their microtubule… 
2000
2000
Identification of ribonucleotide reductase protein R1 as an activator of microtubule nucleation in Xenopus egg mitotic extracts.
Microtubule nucleation on the centrosome and the fungal equivalent, the spindle pole body (SPB), is activated at the onset of… 
1996
1996
Role of gamma-tubulin in mitosis-specific microtubule nucleation from the Schizosaccharomyces pombe spindle pole body.
The ability of the Schizosacchromyces pombe spindle pole body to nucleate microtubules is activated at the onset of mitosis for… 
1980
1980
Guanasone 5'-(alpha,beta-methylene)triphosphate enhances specifically microtubule nucleation and stops the treadmill of tubulin protomers.
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