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Mice, Inbred NOD

Known as: Non Obese Diabetic Mice, Diabetic Mice, Non-Obese, Non Obese Diabetic Mouse 
A strain of non-obese diabetic mice developed in Japan that has been widely studied as a model for T-cell-dependent autoimmune insulin-dependent… 
National Institutes of Health

Related topics

Related topics

7 relations
Diabetes MellitusDiabetes Mellitus, ExperimentalDiabetes Mellitus, Insulin-DependentIn Blood

Broader (1)

Laboratory mice

Papers overview

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Highly Cited
2003
Highly Cited
2003
Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells 1
CD28/B7 blockade leads to exacerbated autoimmune disease in the nonobese diabetic mouse strain as a result of a marked reduction… 
Highly Cited
2003
Highly Cited
2003
TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
CD3-specific antibodies have the unique capacity to restore self-tolerance in established autoimmunity. They induce long-term… 
Highly Cited
1999
Highly Cited
1999
Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses
Highly Cited
1995
Highly Cited
1995
Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
Insulin-dependent diabetes mellitus (IDDM) is thought to be an immunologically mediated disease resulting in the complete… 
Review
1995
Review
1995
Hyperglycemia and Diabetic Kidney Disease: The Case for Transforming Growth Factor–β as a Key Mediator
Renal cells are a rich source of transforming growth factor (TGF)-β, and they serve as targets for its actions. Our hypothesis… 
Highly Cited
1993
Highly Cited
1993
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice
Beginning at the time of insulitis (7 wk of age), CD4+ and CD8+ mature thymocytes from nonobese diabetic (NOD) mice exhibit a… 
Review
1992
Review
1992
The murine autoimmune diabetes model: NOD and related strains.
Highly Cited
1987
Highly Cited
1987
Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells
We have developed a model of syngeneic adoptive transfer for type I diabetes mellitus of NOD mice. This model consists in… 
Review
1982
Review
1982
The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies.
Highly Cited
1982
Highly Cited
1982
Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins
Insulin-dependent diabetic (IDD) patients have a high prevalence of circulating autoantibodies against islet of Langerhans cells… 
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