Mevalonate

 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The YAP and TAZ mediators of the Hippo pathway (hereafter called YAP/TAZ) promote tissue proliferation and organ growth. However… (More)
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Highly Cited
2012
Highly Cited
2012
p53 is a frequent target for mutation in human tumors, and mutant p53 proteins can actively contribute to tumorigenesis. We… (More)
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Review
2011
Review
2011
The mevalonate pathway accounts for conversion of acetyl-CoA to isopentenyl 5-diphosphate, the versatile precursor of… (More)
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Review
2007
Review
2007
The recently discovered non-mevalonate biosynthetic route to isoprenoid precursors is an essential metabolic pathway in plants… (More)
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Review
2004
Review
2004
The mevalonate pathway for the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate (IPP) and… (More)
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Highly Cited
2003
Highly Cited
2003
T lymphocytes expressing the T cell receptor (TCR)-gammadelta recognize unknown antigens on tumor cells. Here we identify… (More)
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Review
1999
Review
1999
1 Isoprenoid biosynthesis 1.1 The mevalonate route to isopentenyl diphosphate 1.2 Isoprenoid biosynthesis in higher plants: some… (More)
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Highly Cited
1999
Highly Cited
1999
Nitrogen-containing bisphosphonates were shown to cause macrophage apoptosis by inhibiting enzymes in the biosynthetic pathway… (More)
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Highly Cited
1998
Highly Cited
1998
Bisphosphonates are currently the most important class of antiresorptive drugs used for the treatment of metabolic bone diseases… (More)
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Review
1990
Review
1990
The mevalonate pathway produces isoprenoids that are vital for diverse cellular functions, ranging from cholesterol synthesis to… (More)
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