Mevalonic Acid

Known as: Acid, Mevalonic, Mevalonic Acid [Chemical/Ingredient], Pentanoic acid, 3,5-dihydroxy-3-methyl- 
A dihydroxy monocarboxylic acid and precursor in the biosynthetic pathway known as the mevalonate pathway, which produces terpenes and steroids that… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
0204019562016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Isopentenyl diphosphate (IPP) is produced via two independent biosynthetic pathways in higher plants: the mevalonate (MVA… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
2002
2002
Once the newly synthesized surface (S)-layer glycoprotein of the halophilic archaeaon Haloferax volcanii has traversed the plasma… (More)
  • figure 1
  • figure 4
  • figure 2
  • figure 3
  • figure 6
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Recent studies have reported that hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors have vasculoprotective effects… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Bisphosphonates are currently the most important class of antiresorptive drugs used for the treatment of metabolic bone diseases… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
OBJECTIVE Mevalonic aciduria is a consequence of the deficiency of mevalonate kinase, the first enzyme after 3-hydroxy-3… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Synchronization of mammalian cells is essential for investigations involving cell proliferation. A simple method for obtaining… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1988
1988
Previous work from this laboratory has shown that a derivative of mevalonic acid is post-translationally incorporated into a… (More)
Is this relevant?
1986
1986
A two-year-old boy presented with severe failure to thrive, developmental delay, anemia, hepatosplenomegaly, central cataracts… (More)
Is this relevant?
1984
1984
Previous studies have identified several cellular requirements for mevalonic acid that appear unrelated to cholesterol, dolichol… (More)
Is this relevant?
1959
1959
In t,he enzymatic synthesis of squalene from mevalonic acid, ATP is one of the required cofactors (1, 2). This finding led to the… (More)
  • table I
  • figure 1
  • table II
  • figure 2
  • table III
Is this relevant?