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6-fluoromevalonate

National Institutes of Health

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Mevalonate

Papers overview

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2016
2016
Abstract 3690: Metabolic regulation of mutant p53 stability by the mevalonate pathway
Introduction: Mutations in the p53 gene are mostly missense mutations and result in accumulation of dysfunctional p53 protein in… 
Highly Cited
1997
Highly Cited
1997
Pharmacological control of the mevalonate pathway: effect on arterial smooth muscle cell proliferation.
The mevalonate (MVA) pathway is involved in cell proliferation. We investigated drugs acting at different enzymatic steps on rat… 
1997
1997
[Pharmacological control of biosynthesis pathway of mevalonate: effect on the proliferation of arterial smooth muscle cells].
The role of mevalonic acid (MVA) and its products (isoprenoids) in cell proliferation prompted us to investigate the effect of… 
Highly Cited
1990
Highly Cited
1990
Inhibition by 6-fluoromevalonate demonstrates that mevalonate or one of the mevalonate phosphates is necessary for lymphocyte proliferation.
1986
1986
Cantharidin biosynthesis in a blister beetle: Inhibition by 6-fluoromevalonate causes chemical disarmament
Biosynthesis of cantharidin in a blister beetle,Lytta polita, is effectively inhibited by 6-fluoromevalonate. Inhibition is… 
1985
1985
Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate.
6-Fluoromevalonate blocks the incorporation of mevalonic acid, but not that of isopentenyl pyrophosphate, into non-saponifiable… 
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