FAQ

Methadyl Acetate

Known as: 6-(Dimethylamino)-4,4-Diphenyl-3-Heptanol Acetate, Methadyl Acetate [Chemical/Ingredient], Acetylmethadol 
A narcotic analgesic with a long onset and duration of action.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2016
0102019512015

Related topics

Related topics

20 relations

Narrower (7)

1 alpha-acetyldinormethadolAlphacetylmethadolLevomethadyl AcetateLevomethadyl Acetate Hydrochloride
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Broader (4)

Analgesics, OpioidMethadoneNarcotic Analgesicssynthetic opioids
In BloodLevomethadylagonistsanalogs & derivatives
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Methadyl Acetate
In Blood
Methadone
chemical synthesis
Analgesics, Opioid
Levomethadyl Acetate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Predictors of retention in methadone programs: a signal detection analysis.
Retention in Opioid Agonist Therapy (OAT) is associated with reductions in substance use, HIV risk behavior, and criminal… (More)
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Highly Cited
2002
Highly Cited
2002
Influence of opioid agonists on cardiac human ether-a-go-go-related gene K(+) currents.
We have evaluated the ability of various opioid agonists, including methadone, L-alpha-acetylmethadol (LAAM), fentanyl… (More)
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1999
1999
Enhancement mu opioid antinociception by oral delta9-tetrahydrocannabinol: dose-response analysis and receptor identification.
The antinociceptive effects of various mu opioids given p.o. alone and in combination with Delta-9-tetrahydrocannabinol (Delta9… (More)
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1997
1997
The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone.
The N-demethylation of LAAM, norLAAM, and methadone has been investigated in human liver microsomes and microsomes containing… (More)
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1995
1995
Particular ability of cytochromes P450 3A to form inhibitory P450-iron-metabolite complexes upon metabolic oxidation of aminodrugs.
The ability of 21 drugs containing an amine function to form inhibitory P450-iron-metabolite complexes absorbing around 455 nm… (More)
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1993
1993
Agonist and antagonist effects of mixed action opioids in the pigeon drug discrimination procedure: influence of training dose, intrinsic efficacy and interanimal differences.
The stimulus effects of selective, high efficacy mu opioids and mixed action opioids with varying degrees of intrinsic efficacy… (More)
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1980
1980
A cooperative clinical study of methadyl acetate. II. Friday-only regimen.
We conducted an open clinical trial of the feasibility of maintaining heroin addicts by administering methadone hydrochloride on… (More)
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1978
1978
A cooperative clinical study of methadyl acetate. I. Three-times-a-week regimen.
This was an open clinical trial of methadyl acetate (LAAM) compared with methadone in the maintenance of 636 heroin addicts who… (More)
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1977
1977
Methadyl acetate and methadone. An open comparison.
Heroin addicts were recruited for a 14-week open clinical comparison of methadone hydrochloride and methadyl acetate. Patients… (More)
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1976
1976
Methadyl acetate and methadone as maintenance treatments for heroin addicts. A veterans administration cooperative study.
This was a double-blind comparison of methadyl acetate and two dose levels of methadone hydrochloride in the maintenance of 430… (More)
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