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Analgesics, Opioid
Known as:
OPIOID ANALGESICS
, opioid analgesic
, analgesics opioid
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Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.
National Institutes of Health
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Related topics
Related topics
50 relations
Narrower (45)
1 ML Nalbuphine Hydrochloride 10 MG/ML Injection
10 ML Morphine Sulfate 1 MG/ML Injection
24 HR tramadol hydrochloride 100 MG Extended Release Oral Tablet
24 HR tramadol hydrochloride 200 MG Extended Release Oral Tablet [Ryzolt]
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In Blood
Narcotics
agonists
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Structure-based discovery of opioid analgesics with reduced side effects
A. Manglik
,
Henry Lin
,
+17 authors
B. Shoichet
Nature
2016
Corpus ID: 2726373
Morphine is an alkaloid from the opium poppy used to treat pain. The potentially lethal side effects of morphine and related…
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Review
2016
Review
2016
Opioid Abuse in Chronic Pain--Misconceptions and Mitigation Strategies.
N. Volkow
,
A. Mclellan
New England Journal of Medicine
2016
Corpus ID: 2211765
Chronic pain not caused by cancer is among the most prevalent and debilitating medical conditions but also among the most…
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Highly Cited
2015
Highly Cited
2015
Trends in opioid analgesic abuse and mortality in the United States.
R. Dart
,
H. Surratt
,
+4 authors
Jody L. Green
New England Journal of Medicine
2015
Corpus ID: 2153787
BACKGROUND The use of prescription opioid medications has increased greatly in the United States during the past two decades; in…
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Review
2008
Review
2008
OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines.
W. Zhang
,
R. Moskowitz
,
+13 authors
P. Tugwell
Osteoarthritis and Cartilage
2008
Corpus ID: 9318699
Highly Cited
2006
Highly Cited
2006
Increasing deaths from opioid analgesics in the United States
L. Paulozzi
,
D. Budnitz
,
Yongli Xi
Pharmacoepidemiology and Drug Safety
2006
Corpus ID: 16121594
Since 1990, numerous jurisdictions in the United States (US) have reported increases in drug poisoning mortality. During the same…
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Highly Cited
2005
Highly Cited
2005
Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial
R. Patchell
,
P. Tibbs
,
+5 authors
B. Young
The Lancet
2005
Corpus ID: 7761862
Review
2000
Review
2000
Trends in medical use and abuse of opioid analgesics.
D. Joranson
,
K. Ryan
,
A. Gilson
,
J. L. Dahl
JAMA
2000
Corpus ID: 1375459
CONTEXT Pain often is inadequately treated due in part to reluctance about using opioid analgesics and fear that they will be…
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Review
1993
Review
1993
Pharmacological mechanisms of opioid analgesics.
G. Pasternak
Clinical neuropharmacology
1993
Corpus ID: 11563177
The description of multiple classes of opioid receptors has had a major impact on our understanding of the mechanisms of…
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Highly Cited
1992
Highly Cited
1992
Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.
R. Raffa
,
E. Friderichs
,
W. Reimann
,
R. Shank
,
E. Codd
,
J. L. Vaught
Journal of Pharmacology and Experimental…
1992
Corpus ID: 43594164
Tramadol hydrochloride produced dose-related antinociception in mouse abdominal constriction [ED50 = 1.9 (1.2-2.6) mg/kg i.p…
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Review
1992
Review
1992
Grading the severity of chronic pain
M. Korff
,
J. Ormel
,
F. Keefe
,
S. Dworkin
Pain
1992
Corpus ID: 34557274
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